BRD-K28428262_S1084_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K28428262_S1084_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACLY ATP citrate lyase
AFF1 AF4/FMR2 family, member 1
AK4 adenylate kinase 4
BEX1 brain expressed, X-linked 1
C5ORF30 chromosome 5 open reading frame 30
CCNG2 cyclin G2
CD24 CD24 molecule
CLU clusterin
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL12 chemokine (C-X-C motif) ligand 12
DEPTOR DEP domain containing MTOR-interacting protein
DMXL1 Dmx-like 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EGF epidermal growth factor
EMC2 ER membrane protein complex subunit 2
ENOPH1 enolase-phosphatase 1
GBP1 guanylate binding protein 1, interferon-inducible
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HACD2 3-hydroxyacyl-CoA dehydratase 2
HLTF helicase-like transcription factor
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ITGAV integrin, alpha V
KNG1 kininogen 1
LEPR leptin receptor
MAN1A1 mannosidase, alpha, class 1A, member 1
MAPT microtubule-associated protein tau
NAMPT nicotinamide phosphoribosyltransferase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NID2 nidogen 2 (osteonidogen)
NPR3 natriuretic peptide receptor 3
NRIP1 nuclear receptor interacting protein 1
PDZK1 PDZ domain containing 1
PON2 paraoxonase 2
RHOB ras homolog family member B
RHOBTB3 Rho-related BTB domain containing 3
RPL38 ribosomal protein L38
S100A12 S100 calcium binding protein A12
S100A7 S100 calcium binding protein A7
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELL selectin L
SEPT11 septin 11
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
UBE2A ubiquitin-conjugating enzyme E2A
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ADORA2B adenosine A2b receptor
ALOX5 arachidonate 5-lipoxygenase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CD1E CD1e molecule
CD9 CD9 molecule
CNPY3 canopy FGF signaling regulator 3
COL6A2 collagen, type VI, alpha 2
CPVL carboxypeptidase, vitellogenic-like
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMBT1 deleted in malignant brain tumors 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPT dermatopontin
DUSP4 dual specificity phosphatase 4
FAM134B family with sequence similarity 134, member B
FCGBP Fc fragment of IgG binding protein
FOSL1 FOS-like antigen 1
HBEGF heparin-binding EGF-like growth factor
HDAC9 histone deacetylase 9
HES1 hes family bHLH transcription factor 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KLF4 Kruppel-like factor 4 (gut)
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LTB lymphotoxin beta (TNF superfamily, member 3)
LYZ lysozyme
MSLN mesothelin
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC4 mucin 4, cell surface associated
MX1 MX dynamin-like GTPase 1
NMU neuromedin U
OLFM4 olfactomedin 4
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNH1 ribonuclease/angiogenin inhibitor 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
SPINK4 serine peptidase inhibitor, Kazal type 4
TACC2 transforming, acidic coiled-coil containing protein 2
WFDC2 WAP four-disulfide core domain 2