BRD-K28366633_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K28366633_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AK1 adenylate kinase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
C1QA complement component 1, q subcomponent, A chain
CACYBP calcyclin binding protein
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DLX2 distal-less homeobox 2
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DSP desmoplakin
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
HAPLN1 hyaluronan and proteoglycan link protein 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPE1 heat shock 10kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER5 immediate early response 5
JMJD6 jumonji domain containing 6
KLF4 Kruppel-like factor 4 (gut)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
ODC1 ornithine decarboxylase 1
OSER1 oxidative stress responsive serine-rich 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PIR pirin (iron-binding nuclear protein)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAP1 small ArfGAP 1
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SQSTM1 sequestosome 1
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM97 transmembrane protein 97
TPD52L1 tumor protein D52-like 1
TUBB2A tubulin, beta 2A class IIa
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
WWP1 WW domain containing E3 ubiquitin protein ligase 1

decreased expression

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
AZU1 azurocidin 1
CCL5 chemokine (C-C motif) ligand 5
CCNE2 cyclin E2
CDA cytidine deaminase
CDK1 cyclin-dependent kinase 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHSY1 chondroitin sulfate synthase 1
CPM carboxypeptidase M
CTSG cathepsin G
DACH1 dachshund family transcription factor 1
GPRC5B G protein-coupled receptor, class C, group 5, member B
GPX1 glutathione peroxidase 1
GRWD1 glutamate-rich WD repeat containing 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IFITM1 interferon induced transmembrane protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDE2A phosphodiesterase 2A, cGMP-stimulated
PLIN1 perilipin 1
PODXL podocalyxin-like
PRKCD protein kinase C, delta
TFPI2 tissue factor pathway inhibitor 2
TSPAN12 tetraspanin 12
VSNL1 visinin-like 1