BRD-K28366633_-666_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

163 genes differentially expressed following the BRD-K28366633_-666_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG1 adhesion G protein-coupled receptor G1
AMDHD2 amidohydrolase domain containing 2
ANGPTL4 angiopoietin-like 4
CALML3 calmodulin-like 3
CLIC3 chloride intracellular channel 3
COL6A2 collagen, type VI, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CRELD2 cysteine-rich with EGF-like domains 2
CRISP3 cysteine-rich secretory protein 3
DENND1B DENN/MADD domain containing 1B
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FLNC filamin C, gamma
FN1 fibronectin 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GAS6 growth arrest-specific 6
GSE1 Gse1 coiled-coil protein
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPB8 heat shock 22kDa protein 8
IER5 immediate early response 5
IGFBP6 insulin-like growth factor binding protein 6
IGHM immunoglobulin heavy constant mu
IL1R2 interleukin 1 receptor, type II
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JAM3 junctional adhesion molecule 3
KRT19 keratin 19, type I
MAST4 microtubule associated serine/threonine kinase family member 4
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PDZK1IP1 PDZK1 interacting protein 1
PLXNB2 plexin B2
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POPDC3 popeye domain containing 3
PPIB peptidylprolyl isomerase B (cyclophilin B)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDC4 syndecan 4
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNX7 sorting nexin 7
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STC1 stanniocalcin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TPBG trophoblast glycoprotein
TTN titin

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD2 abhydrolase domain containing 2
ACOT9 acyl-CoA thioesterase 9
ACSL3 acyl-CoA synthetase long-chain family member 3
ADCY1 adenylate cyclase 1 (brain)
ADD3 adducin 3 (gamma)
AHR aryl hydrocarbon receptor
AMD1 adenosylmethionine decarboxylase 1
ANKRD10 ankyrin repeat domain 10
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BIRC5 baculoviral IAP repeat containing 5
BST2 bone marrow stromal cell antigen 2
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C3 complement component 3
CCNB2 cyclin B2
CCND3 cyclin D3
CDK4 cyclin-dependent kinase 4
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CENPA centromere protein A
CENPU centromere protein U
CIT citron rho-interacting serine/threonine kinase
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CXCL14 chemokine (C-X-C motif) ligand 14
DCK deoxycytidine kinase
DCLK1 doublecortin-like kinase 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ELOVL5 ELOVL fatty acid elongase 5
F3 coagulation factor III (thromboplastin, tissue factor)
FANCI Fanconi anemia, complementation group I
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GRB14 growth factor receptor-bound protein 14
GTPBP8 GTP-binding protein 8 (putative)
HACD3 3-hydroxyacyl-CoA dehydratase 3
HAT1 histone acetyltransferase 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HOXB6 homeobox B6
HOXC6 homeobox C6
HPRT1 hypoxanthine phosphoribosyltransferase 1
IFI6 interferon, alpha-inducible protein 6
IGFBP7 insulin-like growth factor binding protein 7
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IRS1 insulin receptor substrate 1
JAG1 jagged 1
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
LDHB lactate dehydrogenase B
LEF1 lymphoid enhancer-binding factor 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LHFP lipoma HMGIC fusion partner
LIMS1 LIM and senescent cell antigen-like domains 1
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
MARCKSL1 MARCKS-like 1
MELK maternal embryonic leucine zipper kinase
MET MET proto-oncogene, receptor tyrosine kinase
METTL5 methyltransferase like 5
MITF microphthalmia-associated transcription factor
MT1E metallothionein 1E
MTUS1 microtubule associated tumor suppressor 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NCAPG2 non-SMC condensin II complex, subunit G2
NDRG2 NDRG family member 2
NEK4 NIMA-related kinase 4
NPY neuropeptide Y
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUP107 nucleoporin 107kDa
NUP62 nucleoporin 62kDa
NUSAP1 nucleolar and spindle associated protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PBK PDZ binding kinase
PEG10 paternally expressed 10
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLS1 plastin 1
PON2 paraoxonase 2
PPARG peroxisome proliferator-activated receptor gamma
PPIG peptidylprolyl isomerase G (cyclophilin G)
PRPF4 pre-mRNA processing factor 4
PSD3 pleckstrin and Sec7 domain containing 3
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RRP1B ribosomal RNA processing 1B
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC35E3 solute carrier family 35, member E3
SMS spermine synthase
SNAP23 synaptosomal-associated protein, 23kDa
SORBS3 sorbin and SH3 domain containing 3
SRSF6 serine/arginine-rich splicing factor 6
SSFA2 sperm specific antigen 2
STMN1 stathmin 1
SYBU syntabulin (syntaxin-interacting)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TLK1 tousled-like kinase 1
TM4SF1 transmembrane 4 L six family member 1
TMPO thymopoietin
TOP2A topoisomerase (DNA) II alpha 170kDa
TXNDC9 thioredoxin domain containing 9
USP1 ubiquitin specific peptidase 1
VTCN1 V-set domain containing T cell activation inhibitor 1