BRD-K28366633_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

91 genes differentially expressed following the BRD-K28366633_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
AKAP12 A kinase (PRKA) anchor protein 12
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD10 ankyrin repeat domain 10
ATF3 activating transcription factor 3
C4BPA complement component 4 binding protein, alpha
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
DCN decorin
DDIT3 DNA-damage-inducible transcript 3
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
EIF5A eukaryotic translation initiation factor 5A
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FXYD6 FXYD domain containing ion transport regulator 6
GLUL glutamate-ammonia ligase
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IRF9 interferon regulatory factor 9
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KLHL24 kelch-like family member 24
KRT14 keratin 14, type I
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MAOB monoamine oxidase B
MAT2A methionine adenosyltransferase II, alpha
MT1F metallothionein 1F
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFIL3 nuclear factor, interleukin 3 regulated
ODC1 ornithine decarboxylase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTN pleiotrophin
RHOB ras homolog family member B
RIOK3 RIO kinase 3
RNMT RNA (guanine-7-) methyltransferase
S100A8 S100 calcium binding protein A8
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP4 secreted frizzled-related protein 4
SH3YL1 SH3 and SYLF domain containing 1
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
STK10 serine/threonine kinase 10
SYBU syntabulin (syntaxin-interacting)
TPD52 tumor protein D52
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AURKA aurora kinase A
BASP1 brain abundant, membrane attached signal protein 1
CCNA2 cyclin A2
CCND1 cyclin D1
CCNF cyclin F
CDC25B cell division cycle 25B
CDK1 cyclin-dependent kinase 1
CHERP calcium homeostasis endoplasmic reticulum protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
GTSE1 G-2 and S-phase expressed 1
IGFBP4 insulin-like growth factor binding protein 4
KIF20A kinesin family member 20A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LAMC1 laminin, gamma 1 (formerly LAMB2)
LASP1 LIM and SH3 protein 1
NFIB nuclear factor I/B
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRP1 neuropilin 1
PLA2G16 phospholipase A2, group XVI
PLK1 polo-like kinase 1
SHCBP1 SHC SH2-domain binding protein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TACC3 transforming, acidic coiled-coil containing protein 3
THAP11 THAP domain containing 11
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TMEM2 transmembrane protein 2
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C