BRD-K28360340_TW 37_RMUGS_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

124 genes differentially expressed following the BRD-K28360340_TW 37_RMUGS_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AK4 adenylate kinase 4
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1S complement component 1, s subcomponent
CCNG2 cyclin G2
CXCL8 chemokine (C-X-C motif) ligand 8
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP3 dual specificity phosphatase 3
ENO2 enolase 2 (gamma, neuronal)
ERO1L ERO1-like (S. cerevisiae)
FAM129A family with sequence similarity 129, member A
FAM162A family with sequence similarity 162, member A
FAM57A family with sequence similarity 57, member A
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FLG filaggrin
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GBE1 glucan (1,4-alpha-), branching enzyme 1
GDF15 growth differentiation factor 15
GOLM1 golgi membrane protein 1
H1F0 H1 histone family, member 0
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HOXA5 homeobox A5
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IL6ST interleukin 6 signal transducer
INSIG2 insulin induced gene 2
IQCG IQ motif containing G
JUNB jun B proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KDM5B lysine (K)-specific demethylase 5B
LMO4 LIM domain only 4
LOX lysyl oxidase
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MFAP5 microfibrillar associated protein 5
MOXD1 monooxygenase, DBH-like 1
MSX1 msh homeobox 1
MXI1 MAX interactor 1, dimerization protein
NAMPT nicotinamide phosphoribosyltransferase
NCK1 NCK adaptor protein 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PLAGL1 pleiomorphic adenoma gene-like 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRDX2 peroxiredoxin 2
PSPH phosphoserine phosphatase
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAD23B RAD23 homolog B (S. cerevisiae)
RGS2 regulator of G-protein signaling 2
RNF11 ring finger protein 11
RNMT RNA (guanine-7-) methyltransferase
RRAGD Ras-related GTP binding D
SESN1 sestrin 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPAG4 sperm associated antigen 4
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TMEM45A transmembrane protein 45A
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADIRF adipogenesis regulatory factor
ALDOB aldolase B, fructose-bisphosphate
AMIGO2 adhesion molecule with Ig-like domain 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BPHL biphenyl hydrolase-like (serine hydrolase)
C7 complement component 7
CAV2 caveolin 2
CD9 CD9 molecule
CFD complement factor D (adipsin)
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DENND1B DENN/MADD domain containing 1B
DKK3 dickkopf WNT signaling pathway inhibitor 3
DOCK4 dedicator of cytokinesis 4
EPAS1 endothelial PAS domain protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBP1 fructose-1,6-bisphosphatase 1
FN1 fibronectin 1
GPX2 glutathione peroxidase 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JAG1 jagged 1
JCHAIN joining chain of multimeric IgA and IgM
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MID1 midline 1
NELL2 NEL-like 2 (chicken)
NPIPB3 nuclear pore complex interacting protein family, member B3
NTS neurotensin
OLFM4 olfactomedin 4
PRRC2C proline-rich coiled-coil 2C
RBM34 RNA binding motif protein 34
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SCGB2A2 secretoglobin, family 2A, member 2
SFTPC surfactant protein C
SHB Src homology 2 domain containing adaptor protein B
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
WFDC1 WAP four-disulfide core domain 1