BRD-K28296557_Akt inhibitor IV_CL34_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

123 genes differentially expressed following the BRD-K28296557_Akt inhibitor IV_CL34_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
AKR1C2 aldo-keto reductase family 1, member C2
ANXA1 annexin A1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
BTG1 B-cell translocation gene 1, anti-proliferative
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CSTA cystatin A (stefin A)
CTSS cathepsin S
CYBB cytochrome b-245, beta polypeptide
CYTIP cytohesin 1 interacting protein
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
F11R F11 receptor
FOS FBJ murine osteosarcoma viral oncogene homolog
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GADD45A growth arrest and DNA-damage-inducible, alpha
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HES1 hes family bHLH transcription factor 1
HIST1H2BG histone cluster 1, H2bg
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IL7R interleukin 7 receptor
INSIG1 insulin induced gene 1
JUNB jun B proto-oncogene
KRT15 keratin 15, type I
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KRT7 keratin 7, type II
KYNU kynureninase
LAPTM4B lysosomal protein transmembrane 4 beta
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAL mal, T-cell differentiation protein
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R15A protein phosphatase 1, regulatory subunit 15A
QPCT glutaminyl-peptide cyclotransferase
RGCC regulator of cell cycle
RGS4 regulator of G-protein signaling 4
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SH3YL1 SH3 and SYLF domain containing 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SRGN serglycin
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAR steroidogenic acute regulatory protein
STC2 stanniocalcin 2
STK17B serine/threonine kinase 17b
TACSTD2 tumor-associated calcium signal transducer 2
TLR4 toll-like receptor 4
TMPRSS3 transmembrane protease, serine 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCAN versican
VEGFA vascular endothelial growth factor A
VGLL1 vestigial-like family member 1
VNN1 vanin 1
VTCN1 V-set domain containing T cell activation inhibitor 1
YBX3 Y box binding protein 3

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AHNAK2 AHNAK nucleoprotein 2
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
CA12 carbonic anhydrase XII
CANT1 calcium activated nucleotidase 1
CELF2 CUGBP, Elav-like family member 2
CHRDL1 chordin-like 1
CRABP2 cellular retinoic acid binding protein 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAB crystallin, alpha B
CXCL14 chemokine (C-X-C motif) ligand 14
DCLK1 doublecortin-like kinase 1
ECI2 enoyl-CoA delta isomerase 2
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ETFB electron-transfer-flavoprotein, beta polypeptide
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FCGBP Fc fragment of IgG binding protein
FGFR3 fibroblast growth factor receptor 3
GSTA4 glutathione S-transferase alpha 4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT1 keratin 1, type II
LPL lipoprotein lipase
LYPLA1 lysophospholipase I
MALL mal, T-cell differentiation protein-like
MEOX2 mesenchyme homeobox 2
NRN1 neuritin 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PI3 peptidase inhibitor 3, skin-derived
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SCAND1 SCAN domain containing 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SPINK5 serine peptidase inhibitor, Kazal type 5
SRPX sushi-repeat containing protein, X-linked
STK39 serine threonine kinase 39
TESC tescalcin
TNC tenascin C
TSPAN13 tetraspanin 13
TUBB2A tubulin, beta 2A class IIa
XIST X inactive specific transcript (non-protein coding)