BRD-K28296557_Akt inhibitor IV_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K28296557_Akt inhibitor IV_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CYR61 cysteine-rich, angiogenic inducer, 61
DDIT3 DNA-damage-inducible transcript 3
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM69A family with sequence similarity 69, member A
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
IER2 immediate early response 2
IER5 immediate early response 5
JUNB jun B proto-oncogene
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MYC v-myc avian myelocytomatosis viral oncogene homolog
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
SCGB2A1 secretoglobin, family 2A, member 1
TRIB3 tribbles pseudokinase 3
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
PLTP phospholipid transfer protein
TBC1D16 TBC1 domain family, member 16
TMEM2 transmembrane protein 2