BRD-K28143534_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-K28143534_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C4BPA complement component 4 binding protein, alpha
CES1 carboxylesterase 1
CHI3L2 chitinase 3-like 2
CLC Charcot-Leyden crystal galectin
CLU clusterin
CRISP3 cysteine-rich secretory protein 3
CXCL8 chemokine (C-X-C motif) ligand 8
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
HHEX hematopoietically expressed homeobox
HP haptoglobin
IER3 immediate early response 3
IGFBP4 insulin-like growth factor binding protein 4
IGL immunoglobulin lambda locus
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KRT18 keratin 18, type I
LTF lactotransferrin
MCL1 myeloid cell leukemia 1
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSX1 msh homeobox 1
NELL2 NEL-like 2 (chicken)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ORM1 orosomucoid 1
PEG3 paternally expressed 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RHOB ras homolog family member B
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SMYD3 SET and MYND domain containing 3
SOX4 SRY (sex determining region Y)-box 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TXNL4B thioredoxin-like 4B
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)
ZBTB20 zinc finger and BTB domain containing 20
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ADI1 acireductone dioxygenase 1
ADIRF adipogenesis regulatory factor
AGTR1 angiotensin II receptor, type 1
AQP3 aquaporin 3 (Gill blood group)
C6ORF62 chromosome 6 open reading frame 62
CANT1 calcium activated nucleotidase 1
CCNB2 cyclin B2
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CPB1 carboxypeptidase B1 (tissue)
CXCL14 chemokine (C-X-C motif) ligand 14
DCK deoxycytidine kinase
DPYSL2 dihydropyrimidinase-like 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GJA1 gap junction protein, alpha 1, 43kDa
GOLT1B golgi transport 1B
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
INSIG1 insulin induced gene 1
KCTD12 potassium channel tetramerization domain containing 12
KRT14 keratin 14, type I
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LYPLA1 lysophospholipase I
MYH11 myosin, heavy chain 11, smooth muscle
NOV nephroblastoma overexpressed
NT5DC2 5'-nucleotidase domain containing 2
OLFM4 olfactomedin 4
PBK PDZ binding kinase
PCNA proliferating cell nuclear antigen
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RNASE4 ribonuclease, RNase A family, 4
SNN stannin
TAGLN transgelin
TIGAR TP53 induced glycolysis regulatory phosphatase
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1