BRD-K27665173_PDGF Receptor Tyrosine Kinase Inhibitor I_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

23 genes differentially expressed following the BRD-K27665173_PDGF Receptor Tyrosine Kinase Inhibitor I_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
CCNA2 cyclin A2
CDC25B cell division cycle 25B
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
HEBP1 heme binding protein 1
KIF20A kinesin family member 20A
RGS2 regulator of G-protein signaling 2
SNX7 sorting nexin 7

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
C4BPA complement component 4 binding protein, alpha
CAV1 caveolin 1, caveolae protein, 22kDa
DKK3 dickkopf WNT signaling pathway inhibitor 3
GLUL glutamate-ammonia ligase
IFI27 interferon, alpha-inducible protein 27
KRT19 keratin 19, type I
LGALS3 lectin, galactoside-binding, soluble, 3
RAP1GAP RAP1 GTPase activating protein
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TFPI2 tissue factor pathway inhibitor 2