BRD-K27665173_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

52 genes differentially expressed following the BRD-K27665173_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAA1 acetyl-CoA acyltransferase 1
ADM adrenomedullin
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTG1 B-cell translocation gene 1, anti-proliferative
CD1E CD1e molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
GDF15 growth differentiation factor 15
KYNU kynureninase
LRMP lymphoid-restricted membrane protein
LYZ lysozyme
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSBPL10 oxysterol binding protein-like 10
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDZK1IP1 PDZK1 interacting protein 1
PHGDH phosphoglycerate dehydrogenase
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SGK1 serum/glucocorticoid regulated kinase 1
SIK1 salt-inducible kinase 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SORBS2 sorbin and SH3 domain containing 2
SRGN serglycin
TGFBI transforming growth factor, beta-induced, 68kDa
VAT1 vesicle amine transport 1
WARS tryptophanyl-tRNA synthetase
XPOT exportin, tRNA

decreased expression

Symbol Name
CCNA2 cyclin A2
CD24 CD24 molecule
CDC42 cell division cycle 42
CELF2 CUGBP, Elav-like family member 2
DCK deoxycytidine kinase
F2RL1 coagulation factor II (thrombin) receptor-like 1
GINS1 GINS complex subunit 1 (Psf1 homolog)
GINS2 GINS complex subunit 2 (Psf2 homolog)
HOPX HOP homeobox
IFI16 interferon, gamma-inducible protein 16
KIAA0101 KIAA0101
KIF14 kinesin family member 14
MATN2 matrilin 2
MELK maternal embryonic leucine zipper kinase
PBK PDZ binding kinase
PLK1 polo-like kinase 1
SEPP1 selenoprotein P, plasma, 1
TNNT1 troponin T type 1 (skeletal, slow)
UBE2C ubiquitin-conjugating enzyme E2C