BRD-K27630390_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

46 genes differentially expressed following the BRD-K27630390_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
HIST1H1C histone cluster 1, H1c
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
JAG1 jagged 1
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
MTSS1 metastasis suppressor 1
OLFM4 olfactomedin 4
PRSS3 protease, serine, 3
RALGDS ral guanine nucleotide dissociation stimulator
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SQLE squalene epoxidase
SRGN serglycin
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)

decreased expression

Symbol Name
CALB1 calbindin 1, 28kDa
CAST calpastatin
COL3A1 collagen, type III, alpha 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA2 heat shock 70kDa protein 2
IFRD2 interferon-related developmental regulator 2
IL13RA2 interleukin 13 receptor, alpha 2
MOXD1 monooxygenase, DBH-like 1
PAM peptidylglycine alpha-amidating monooxygenase
PAMR1 peptidase domain containing associated with muscle regeneration 1
PI3 peptidase inhibitor 3, skin-derived
PRKD3 protein kinase D3
RHOBTB3 Rho-related BTB domain containing 3
RPL27A ribosomal protein L27a
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SPRY2 sprouty homolog 2 (Drosophila)