BRD-K27316855_calcitriol_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K27316855_calcitriol_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
ASNS asparagine synthetase (glutamine-hydrolyzing)
BASP1 brain abundant, membrane attached signal protein 1
C10ORF10 chromosome 10 open reading frame 10
C6ORF62 chromosome 6 open reading frame 62
CCNG2 cyclin G2
CD59 CD59 molecule, complement regulatory protein
CDC42 cell division cycle 42
CEMIP cell migration inducing protein, hyaluronan binding
DDIT4 DNA-damage-inducible transcript 4
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPS8 epidermal growth factor receptor pathway substrate 8
F3 coagulation factor III (thromboplastin, tissue factor)
FAM129A family with sequence similarity 129, member A
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSN gelsolin
HMOX1 heme oxygenase 1
HOPX HOP homeobox
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
ITGB4 integrin, beta 4
KRT19 keratin 19, type I
LEPR leptin receptor
LY96 lymphocyte antigen 96
MAGED2 melanoma antigen family D2
MMP1 matrix metallopeptidase 1
NET1 neuroepithelial cell transforming 1
NPC1 Niemann-Pick disease, type C1
NRIP1 nuclear receptor interacting protein 1
PDGFA platelet-derived growth factor alpha polypeptide
PLA2G16 phospholipase A2, group XVI
PPAP2B phosphatidic acid phosphatase type 2B
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP1 retinol binding protein 1, cellular
RPL37A ribosomal protein L37a
SEPP1 selenoprotein P, plasma, 1
SERINC3 serine incorporator 3
SLC38A1 solute carrier family 38, member 1
SMAD3 SMAD family member 3
SRGN serglycin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBD thrombomodulin
TM4SF1 transmembrane 4 L six family member 1
TPBG trophoblast glycoprotein
UGCG UDP-glucose ceramide glucosyltransferase
VGLL4 vestigial-like family member 4
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CDC25A cell division cycle 25A
CKB creatine kinase, brain
EIF5A eukaryotic translation initiation factor 5A
LYZ lysozyme
MTCL1 microtubule crosslinking factor 1
PA2G4 proliferation-associated 2G4, 38kDa
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
PRPF4 pre-mRNA processing factor 4
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A4 S100 calcium binding protein A4
SFRP1 secreted frizzled-related protein 1
TGFBR3 transforming growth factor, beta receptor III
XIST X inactive specific transcript (non-protein coding)