BRD-K26997899_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K26997899_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
FHL2 four and a half LIM domains 2
GAS6 growth arrest-specific 6
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KIAA0226L KIAA0226-like
MFAP5 microfibrillar associated protein 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
S100A8 S100 calcium binding protein A8
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
BAMBI BMP and activin membrane-bound inhibitor
DDIT4 DNA-damage-inducible transcript 4
DHRS3 dehydrogenase/reductase (SDR family) member 3
ETV1 ets variant 1
GDF15 growth differentiation factor 15
HOXA5 homeobox A5
IER3 immediate early response 3
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIR pirin (iron-binding nuclear protein)
PLIN2 perilipin 2
PPARG peroxisome proliferator-activated receptor gamma
SKAP2 src kinase associated phosphoprotein 2
SPP1 secreted phosphoprotein 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
WWTR1 WW domain containing transcription regulator 1