BRD-K26838195_AST1306_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K26838195_AST1306_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM28 ADAM metallopeptidase domain 28
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASMTL acetylserotonin O-methyltransferase-like
BEX1 brain expressed, X-linked 1
CA12 carbonic anhydrase XII
CAPN1 calpain 1, (mu/I) large subunit
CCDC92 coiled-coil domain containing 92
CD9 CD9 molecule
CES1 carboxylesterase 1
CTSD cathepsin D
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DHCR24 24-dehydrocholesterol reductase
DMTF1 cyclin D binding myb-like transcription factor 1
EFHC1 EF-hand domain (C-terminal) containing 1
ENO2 enolase 2 (gamma, neuronal)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGFR4 fibroblast growth factor receptor 4
FOSL2 FOS-like antigen 2
FXYD2 FXYD domain containing ion transport regulator 2
GPNMB glycoprotein (transmembrane) nmb
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
IFITM3 interferon induced transmembrane protein 3
IVNS1ABP influenza virus NS1A binding protein
KLF6 Kruppel-like factor 6
MAPT microtubule-associated protein tau
MEIS1 Meis homeobox 1
MUC1 mucin 1, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PARP2 poly (ADP-ribose) polymerase 2
PDZK1IP1 PDZK1 interacting protein 1
PLXNB1 plexin B1
SCG2 secretogranin II
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEPP1 selenoprotein P, plasma, 1
SLC38A6 solute carrier family 38, member 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPP1 secreted phosphoprotein 1
TCTA T-cell leukemia translocation altered
TM9SF3 transmembrane 9 superfamily member 3
TSPAN8 tetraspanin 8
TTC39A tetratricopeptide repeat domain 39A
VAT1 vesicle amine transport 1
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CCND2 cyclin D2
CDC20 cell division cycle 20
CDC42 cell division cycle 42
CHIC2 cysteine-rich hydrophobic domain 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DPYD dihydropyrimidine dehydrogenase
DUSP7 dual specificity phosphatase 7
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FAM129A family with sequence similarity 129, member A
FGFBP1 fibroblast growth factor binding protein 1
GEM GTP binding protein overexpressed in skeletal muscle
GLIPR1 GLI pathogenesis-related 1
GPM6B glycoprotein M6B
HHEX hematopoietically expressed homeobox
HIST1H2BG histone cluster 1, H2bg
HOPX HOP homeobox
IER3 immediate early response 3
IGLL1 immunoglobulin lambda-like polypeptide 1
ISLR immunoglobulin superfamily containing leucine-rich repeat
KRT6B keratin 6B, type II
LMO4 LIM domain only 4
MAGEA3 melanoma antigen family A3
MALL mal, T-cell differentiation protein-like
MELK maternal embryonic leucine zipper kinase
MGP matrix Gla protein
MYCBP MYC binding protein
NELL2 NEL-like 2 (chicken)
NFIB nuclear factor I/B
NT5E 5'-nucleotidase, ecto (CD73)
ORC6 origin recognition complex, subunit 6
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM1 PDZ and LIM domain 1
PDLIM4 PDZ and LIM domain 4
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAT plasminogen activator, tissue
PROM1 prominin 1
PTX3 pentraxin 3, long
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGS2 regulator of G-protein signaling 2
RPL27A ribosomal protein L27a
RPS11 ribosomal protein S11
SCRG1 stimulator of chondrogenesis 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SPTBN1 spectrin, beta, non-erythrocytic 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TESC tescalcin
TM4SF1 transmembrane 4 L six family member 1
TMX4 thioredoxin-related transmembrane protein 4
TRIM2 tripartite motif containing 2
VCAN versican