BRD-K26818574_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K26818574_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLEC2B C-type lectin domain family 2, member B
DDIT4 DNA-damage-inducible transcript 4
EGLN1 egl-9 family hypoxia-inducible factor 1
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
GLRX glutaredoxin (thioltransferase)
GPI glucose-6-phosphate isomerase
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NRN1 neuritin 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOD2 superoxide dismutase 2, mitochondrial
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNIP1 TNFAIP3 interacting protein 1
TSPAN7 tetraspanin 7
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
HSPA1A heat shock 70kDa protein 1A
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
RBP1 retinol binding protein 1, cellular
SPRR3 small proline-rich protein 3