BRD-K26674531_GR-235_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

82 genes differentially expressed following the BRD-K26674531_GR-235_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
APOB apolipoprotein B
C10ORF10 chromosome 10 open reading frame 10
C1QA complement component 1, q subcomponent, A chain
CD24 CD24 molecule
CLDN3 claudin 3
CLDN4 claudin 4
CLU clusterin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNTT DNA nucleotidylexotransferase
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GATA3 GATA binding protein 3
GHR growth hormone receptor
HIST1H1C histone cluster 1, H1c
HMOX1 heme oxygenase 1
ICAM2 intercellular adhesion molecule 2
IFI16 interferon, gamma-inducible protein 16
IGFBP7 insulin-like growth factor binding protein 7
IGHD immunoglobulin heavy constant delta
IL13RA2 interleukin 13 receptor, alpha 2
KRT23 keratin 23, type I
LAMA4 laminin, alpha 4
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MAN1A1 mannosidase, alpha, class 1A, member 1
MTSS1 metastasis suppressor 1
NARFL nuclear prelamin A recognition factor-like
ORM1 orosomucoid 1
RBP4 retinol binding protein 4, plasma
RHOB ras homolog family member B
RNF167 ring finger protein 167
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STX1A syntaxin 1A (brain)
SYT1 synaptotagmin I
TXNL4B thioredoxin-like 4B
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BST2 bone marrow stromal cell antigen 2
C1ORF106 chromosome 1 open reading frame 106
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
EPN2 epsin 2
G0S2 G0/G1 switch 2
GREM1 gremlin 1, DAN family BMP antagonist
HAT1 histone acetyltransferase 1
HES1 hes family bHLH transcription factor 1
HIP1 huntingtin interacting protein 1
IGF1R insulin-like growth factor 1 receptor
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
MOB4 MOB family member 4, phocein
NDN necdin, melanoma antigen (MAGE) family member
NR4A2 nuclear receptor subfamily 4, group A, member 2
PARP2 poly (ADP-ribose) polymerase 2
PDGFD platelet derived growth factor D
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
POSTN periostin, osteoblast specific factor
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRDX2 peroxiredoxin 2
QPRT quinolinate phosphoribosyltransferase
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS2 regulator of G-protein signaling 2
SGCE sarcoglycan, epsilon
SKAP2 src kinase associated phosphoprotein 2
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS2 thrombospondin 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM9SF2 transmembrane 9 superfamily member 2
TNS3 tensin 3
TSPAN8 tetraspanin 8
UFM1 ubiquitin-fold modifier 1
VCAN versican
YME1L1 YME1-like 1 ATPase