BRD-K26241953_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

50 genes differentially expressed following the BRD-K26241953_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AK4 adenylate kinase 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANKRD10 ankyrin repeat domain 10
ASS1 argininosuccinate synthase 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CD58 CD58 molecule
CFB complement factor B
COMP cartilage oligomeric matrix protein
DDAH1 dimethylarginine dimethylaminohydrolase 1
DENND2D DENN/MADD domain containing 2D
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP1 dual specificity phosphatase 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPS8 epidermal growth factor receptor pathway substrate 8
FTH1 ferritin, heavy polypeptide 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
MSX1 msh homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PAM peptidylglycine alpha-amidating monooxygenase
PENK proenkephalin
PLA2G16 phospholipase A2, group XVI
PTX3 pentraxin 3, long
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SQSTM1 sequestosome 1
TLR2 toll-like receptor 2
TPBG trophoblast glycoprotein
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
DUOX2 dual oxidase 2
EIF5A eukaryotic translation initiation factor 5A
FHL1 four and a half LIM domains 1
HMG20B high mobility group 20B
HOPX HOP homeobox
ITGA6 integrin, alpha 6
PMM2 phosphomannomutase 2
RGS5 regulator of G-protein signaling 5
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2