BRD-K26211296_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K26211296_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMD1 adenosylmethionine decarboxylase 1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BSG basigin (Ok blood group)
CA12 carbonic anhydrase XII
CREG1 cellular repressor of E1A-stimulated genes 1
CSRP2 cysteine and glycine-rich protein 2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EFNB2 ephrin-B2
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
FASN fatty acid synthase
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GJA1 gap junction protein, alpha 1, 43kDa
GSTP1 glutathione S-transferase pi 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HILPDA hypoxia inducible lipid droplet-associated
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
LDOC1 leucine zipper, down-regulated in cancer 1
LTF lactotransferrin
MET MET proto-oncogene, receptor tyrosine kinase
NAMPT nicotinamide phosphoribosyltransferase
NKX3-1 NK3 homeobox 1
NT5DC2 5'-nucleotidase domain containing 2
PPAP2B phosphatidic acid phosphatase type 2B
RGS2 regulator of G-protein signaling 2
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
TAGLN2 transgelin 2
TPM4 tropomyosin 4
UBE2S ubiquitin-conjugating enzyme E2S
WAC WW domain containing adaptor with coiled-coil
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CEMIP cell migration inducing protein, hyaluronan binding
CTGF connective tissue growth factor
CXCL12 chemokine (C-X-C motif) ligand 12
DACT1 dishevelled-binding antagonist of beta-catenin 1
DUSP22 dual specificity phosphatase 22
FABP4 fatty acid binding protein 4, adipocyte
GMDS GDP-mannose 4,6-dehydratase
GOLGA8A golgin A8 family, member A
METTL7A methyltransferase like 7A
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PSCA prostate stem cell antigen
RBP1 retinol binding protein 1, cellular
RGS4 regulator of G-protein signaling 4
RPS27L ribosomal protein S27-like
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS1 thrombospondin 1
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)