BRD-K25979535_8009-6730_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K25979535_8009-6730_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CFD complement factor D (adipsin)
CST3 cystatin C
FAM65B family with sequence similarity 65, member B
FHL1 four and a half LIM domains 1
FKBP5 FK506 binding protein 5
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FZD7 frizzled class receptor 7
HBB hemoglobin, beta
HOXC6 homeobox C6
HPRT1 hypoxanthine phosphoribosyltransferase 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
KLF4 Kruppel-like factor 4 (gut)
KRT18 keratin 18, type I
LY75 lymphocyte antigen 75
MGP matrix Gla protein
SAP30 Sin3A-associated protein, 30kDa
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
STK17B serine/threonine kinase 17b
SVIL supervillin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TLR4 toll-like receptor 4
TSPAN8 tetraspanin 8
ZEB2 zinc finger E-box binding homeobox 2

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADGRG1 adhesion G protein-coupled receptor G1
AMPD3 adenosine monophosphate deaminase 3
ATP11B ATPase, class VI, type 11B
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BPHL biphenyl hydrolase-like (serine hydrolase)
CA12 carbonic anhydrase XII
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CREB3L2 cAMP responsive element binding protein 3-like 2
DLK1 delta-like 1 homolog (Drosophila)
FASN fatty acid synthase
FBN2 fibrillin 2
FZD10 frizzled class receptor 10
GLUL glutamate-ammonia ligase
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GSE1 Gse1 coiled-coil protein
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPGDS hematopoietic prostaglandin D synthase
MAP7 microtubule-associated protein 7
MGLL monoglyceride lipase
MMP10 matrix metallopeptidase 10
MREG melanoregulin
MTSS1 metastasis suppressor 1
NRIP1 nuclear receptor interacting protein 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDZD2 PDZ domain containing 2
PEG3 paternally expressed 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PPAP2B phosphatidic acid phosphatase type 2B
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
RAB38 RAB38, member RAS oncogene family
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC1 syndecan 1
TFPI2 tissue factor pathway inhibitor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3