BRD-K25905511_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K25905511_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DEPTOR DEP domain containing MTOR-interacting protein
FGFR2 fibroblast growth factor receptor 2
GAL galanin/GMAP prepropeptide
GRB7 growth factor receptor-bound protein 7
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H2BG histone cluster 1, H2bg
HOXC6 homeobox C6
HPCAL1 hippocalcin-like 1
HSPA1A heat shock 70kDa protein 1A
INHBA inhibin, beta A
IPO13 importin 13
ITM2C integral membrane protein 2C
KRT7 keratin 7, type II
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
MT1G metallothionein 1G
MT1M metallothionein 1M
MT1X metallothionein 1X
NNMT nicotinamide N-methyltransferase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSBPL10 oxysterol binding protein-like 10
PCDH9 protocadherin 9
PROM1 prominin 1
PXMP2 peroxisomal membrane protein 2, 22kDa
QPCT glutaminyl-peptide cyclotransferase
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
REEP1 receptor accessory protein 1
RTN1 reticulon 1
S100A8 S100 calcium binding protein A8
SGK1 serum/glucocorticoid regulated kinase 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFBI transforming growth factor, beta-induced, 68kDa
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPD52L1 tumor protein D52-like 1

decreased expression

Symbol Name
CAB39 calcium binding protein 39
CD24 CD24 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN2A cyclin-dependent kinase inhibitor 2A
CELF2 CUGBP, Elav-like family member 2
CTGF connective tissue growth factor
CTSH cathepsin H
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
F3 coagulation factor III (thromboplastin, tissue factor)
FBLN1 fibulin 1
FLNA filamin A, alpha
GSTA4 glutathione S-transferase alpha 4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT4 keratin 4, type II
LCN2 lipocalin 2
MAGED2 melanoma antigen family D2
MARCKS myristoylated alanine-rich protein kinase C substrate
MSX1 msh homeobox 1
MUC1 mucin 1, cell surface associated
MX2 MX dynamin-like GTPase 2
PER3 period circadian clock 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLS3 plastin 3
PODXL podocalyxin-like
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SNX7 sorting nexin 7
TACSTD2 tumor-associated calcium signal transducer 2
TSPAN8 tetraspanin 8
TUBB2A tubulin, beta 2A class IIa