BRD-K25731886_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

108 genes differentially expressed following the BRD-K25731886_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALB albumin
AMIGO2 adhesion molecule with Ig-like domain 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG2 BTG family, member 2
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CD200 CD200 molecule
CD24 CD24 molecule
CECR1 cat eye syndrome chromosome region, candidate 1
CLEC2B C-type lectin domain family 2, member B
COL15A1 collagen, type XV, alpha 1
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
DEPTOR DEP domain containing MTOR-interacting protein
DSG2 desmoglein 2
EDNRA endothelin receptor type A
ESR1 estrogen receptor 1
FAM69A family with sequence similarity 69, member A
FGL2 fibrinogen-like 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GUSBP11 glucuronidase, beta pseudogene 11
HHEX hematopoietically expressed homeobox
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HOPX HOP homeobox
HOXB2 homeobox B2
IFI16 interferon, gamma-inducible protein 16
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JCHAIN joining chain of multimeric IgA and IgM
KRT15 keratin 15, type I
LPAR6 lysophosphatidic acid receptor 6
MAN1A1 mannosidase, alpha, class 1A, member 1
MEF2C myocyte enhancer factor 2C
MTSS1 metastasis suppressor 1
NID2 nidogen 2 (osteonidogen)
NT5E 5'-nucleotidase, ecto (CD73)
PEG3 paternally expressed 3
PLA2G16 phospholipase A2, group XVI
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPAP2B phosphatidic acid phosphatase type 2B
RALB v-ral simian leukemia viral oncogene homolog B
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SERINC5 serine incorporator 5
SPARCL1 SPARC-like 1 (hevin)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SULF1 sulfatase 1
TBC1D31 TBC1 domain family, member 31
TBX3 T-box 3
TMEM123 transmembrane protein 123
TOX3 TOX high mobility group box family member 3
TSPAN7 tetraspanin 7
XIST X inactive specific transcript (non-protein coding)
ZBED2 zinc finger, BED-type containing 2

decreased expression

Symbol Name
BST2 bone marrow stromal cell antigen 2
C6ORF62 chromosome 6 open reading frame 62
CDK6 cyclin-dependent kinase 6
COASY CoA synthase
COCH cochlin
COL1A1 collagen, type I, alpha 1
CTTN cortactin
CYBA cytochrome b-245, alpha polypeptide
DLC1 DLC1 Rho GTPase activating protein
FAM46A family with sequence similarity 46, member A
FKSG49 FKSG49
FLOT2 flotillin 2
FOLR1 folate receptor 1 (adult)
FPGS folylpolyglutamate synthase
HOXC6 homeobox C6
IL7R interleukin 7 receptor
KIAA0100 KIAA0100
LAMC1 laminin, gamma 1 (formerly LAMB2)
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LOX lysyl oxidase
LTBP3 latent transforming growth factor beta binding protein 3
MAGED1 melanoma antigen family D1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PENK proenkephalin
PKM pyruvate kinase, muscle
PLEC plectin
PRKCA protein kinase C, alpha
PRR7 proline rich 7 (synaptic)
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SORBS3 sorbin and SH3 domain containing 3
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STXBP1 syntaxin binding protein 1
STXBP2 syntaxin binding protein 2
TAGLN2 transgelin 2
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMED3 transmembrane emp24 protein transport domain containing 3
UGCG UDP-glucose ceramide glucosyltransferase
ZFP36L2 ZFP36 ring finger protein-like 2
ZMAT3 zinc finger, matrin-type 3