BRD-K25650355_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K25650355_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN1 actinin, alpha 1
ALOX5 arachidonate 5-lipoxygenase
CLIC4 chloride intracellular channel 4
CST3 cystatin C
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
FOXC1 forkhead box C1
MICB MHC class I polypeptide-related sequence B
NR2F2 nuclear receptor subfamily 2, group F, member 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SRRM2 serine/arginine repetitive matrix 2
TACSTD2 tumor-associated calcium signal transducer 2

decreased expression

Symbol Name
ADA adenosine deaminase
ASCL1 achaete-scute family bHLH transcription factor 1
ASPN asporin
BEX1 brain expressed, X-linked 1
CNPY3 canopy FGF signaling regulator 3
ESRP1 epithelial splicing regulatory protein 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
JAM3 junctional adhesion molecule 3
LAMP5 lysosomal-associated membrane protein family, member 5
LRRC15 leucine rich repeat containing 15
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NREP neuronal regeneration related protein
POSTN periostin, osteoblast specific factor
RGS5 regulator of G-protein signaling 5
SCG5 secretogranin V
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SWAP70 SWAP switching B-cell complex 70kDa subunit