BRD-K25591257_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K25591257_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4A ADP-ribosylation factor-like 4A
C14ORF132 chromosome 14 open reading frame 132
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CLIC5 chloride intracellular channel 5
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DKK3 dickkopf WNT signaling pathway inhibitor 3
FAM129A family with sequence similarity 129, member A
FSD1 fibronectin type III and SPRY domain containing 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA8 heat shock 70kDa protein 8
KLF4 Kruppel-like factor 4 (gut)
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
STK39 serine threonine kinase 39
TMSB15A thymosin beta 15a
TPST2 tyrosylprotein sulfotransferase 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CHI3L2 chitinase 3-like 2
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FERMT2 fermitin family member 2
GBP1 guanylate binding protein 1, interferon-inducible
GPSM2 G-protein signaling modulator 2
IFRD2 interferon-related developmental regulator 2
IGHM immunoglobulin heavy constant mu
KANK1 KN motif and ankyrin repeat domains 1
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KRT7 keratin 7, type II
KYNU kynureninase
LTF lactotransferrin
MFAP5 microfibrillar associated protein 5
MKI67 marker of proliferation Ki-67
NFIB nuclear factor I/B
PCSK1 proprotein convertase subtilisin/kexin type 1
PLK1 polo-like kinase 1
PSRC1 proline/serine-rich coiled-coil 1
REG3A regenerating islet-derived 3 alpha
RNF167 ring finger protein 167
S100A2 S100 calcium binding protein A2
SEPP1 selenoprotein P, plasma, 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOX9 SRY (sex determining region Y)-box 9
SPTBN1 spectrin, beta, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPX sushi-repeat containing protein, X-linked
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TOP2A topoisomerase (DNA) II alpha 170kDa