BRD-K25340465_OSI-930_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K25340465_OSI-930_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
BPHL biphenyl hydrolase-like (serine hydrolase)
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHL1 cell adhesion molecule L1-like
COL5A2 collagen, type V, alpha 2
CRISP3 cysteine-rich secretory protein 3
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
GPM6B glycoprotein M6B
GREM1 gremlin 1, DAN family BMP antagonist
LOXL1 lysyl oxidase-like 1
MAL mal, T-cell differentiation protein
NEBL nebulette
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAC8 placenta-specific 8
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTPRC protein tyrosine phosphatase, receptor type, C
RAB4A RAB4A, member RAS oncogene family
RCAN1 regulator of calcineurin 1
SCCPDH saccharopine dehydrogenase (putative)
SCGB2A2 secretoglobin, family 2A, member 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C10ORF10 chromosome 10 open reading frame 10
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLDN18 claudin 18
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
DLC1 DLC1 Rho GTPase activating protein
EFNB2 ephrin-B2
EFS embryonal Fyn-associated substrate
EPHA3 EPH receptor A3
FN1 fibronectin 1
GDF15 growth differentiation factor 15
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
HAPLN1 hyaluronan and proteoglycan link protein 1
HEBP1 heme binding protein 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPB8 heat shock 22kDa protein 8
PEG3 paternally expressed 3
PLBD1 phospholipase B domain containing 1
PMM2 phosphomannomutase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
REEP1 receptor accessory protein 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
SFTPA2 surfactant protein A2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
TBX2 T-box 2
TMEM100 transmembrane protein 100
TSC22D1 TSC22 domain family, member 1