BRD-K25320246_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K25320246_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
C5AR1 complement component 5a receptor 1
CA12 carbonic anhydrase XII
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CRNN cornulin
CX3CR1 chemokine (C-X3-C motif) receptor 1
DUSP2 dual specificity phosphatase 2
FADS1 fatty acid desaturase 1
FGR FGR proto-oncogene, Src family tyrosine kinase
FPR1 formyl peptide receptor 1
GPATCH8 G patch domain containing 8
IGHD immunoglobulin heavy constant delta
IL1RN interleukin 1 receptor antagonist
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
IRS2 insulin receptor substrate 2
KRT1 keratin 1, type II
KRT6A keratin 6A, type II
PODXL podocalyxin-like
RGS2 regulator of G-protein signaling 2
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
CDH3 cadherin 3, type 1, P-cadherin (placental)
COL15A1 collagen, type XV, alpha 1
COL16A1 collagen, type XVI, alpha 1
COMP cartilage oligomeric matrix protein
EPHA3 EPH receptor A3
FGF13 fibroblast growth factor 13
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GPNMB glycoprotein (transmembrane) nmb
HAPLN1 hyaluronan and proteoglycan link protein 1
HHEX hematopoietically expressed homeobox
HOXC6 homeobox C6
INHBA inhibin, beta A
LAGE3 L antigen family, member 3
LAMP5 lysosomal-associated membrane protein family, member 5
MMP9 matrix metallopeptidase 9
NFIB nuclear factor I/B
NPY neuropeptide Y
PLAU plasminogen activator, urokinase
PROM1 prominin 1
SFRP4 secreted frizzled-related protein 4
SOX9 SRY (sex determining region Y)-box 9
STOM stomatin
TCF4 transcription factor 4
THBS2 thrombospondin 2