BRD-K25144184_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K25144184_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BMP4 bone morphogenetic protein 4
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COCH cochlin
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHRS7 dehydrogenase/reductase (SDR family) member 7
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FAM129A family with sequence similarity 129, member A
GPM6B glycoprotein M6B
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA1A heat shock 70kDa protein 1A
HSPH1 heat shock 105kDa/110kDa protein 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KLK11 kallikrein-related peptidase 11
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LTF lactotransferrin
LYN LYN proto-oncogene, Src family tyrosine kinase
MAN1A1 mannosidase, alpha, class 1A, member 1
MMD monocyte to macrophage differentiation-associated
NELL2 NEL-like 2 (chicken)
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
OLFM4 olfactomedin 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLIN2 perilipin 2
PPP1R16B protein phosphatase 1, regulatory subunit 16B
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPL39L ribosomal protein L39-like
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM100 transmembrane protein 100
TSPYL5 TSPY-like 5
UPP1 uridine phosphorylase 1
VIM vimentin
XIST X inactive specific transcript (non-protein coding)
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
AGR2 anterior gradient 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CCND1 cyclin D1
CLIC4 chloride intracellular channel 4
CXCL9 chemokine (C-X-C motif) ligand 9
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSP desmoplakin
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FXYD3 FXYD domain containing ion transport regulator 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
KIAA0101 KIAA0101
LGALS2 lectin, galactoside-binding, soluble, 2
LTBP1 latent transforming growth factor beta binding protein 1
MEIS1 Meis homeobox 1
PAM peptidylglycine alpha-amidating monooxygenase
PDGFA platelet-derived growth factor alpha polypeptide
PFN2 profilin 2
PODXL podocalyxin-like
POSTN periostin, osteoblast specific factor
RGS1 regulator of G-protein signaling 1
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
SCARB2 scavenger receptor class B, member 2
SEPP1 selenoprotein P, plasma, 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
TFF3 trefoil factor 3 (intestinal)
TPM4 tropomyosin 4
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon