BRD-K24754728_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K24754728_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADIRF adipogenesis regulatory factor
AK1 adenylate kinase 1
BAG1 BCL2-associated athanogene
C6ORF62 chromosome 6 open reading frame 62
C8ORF4 chromosome 8 open reading frame 4
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLU clusterin
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DACH1 dachshund family transcription factor 1
EIF5A eukaryotic translation initiation factor 5A
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPCAM epithelial cell adhesion molecule
FBXO11 F-box protein 11
FKBP14 FK506 binding protein 14, 22 kDa
FOLR1 folate receptor 1 (adult)
FZD10 frizzled class receptor 10
HIST1H1C histone cluster 1, H1c
HLF hepatic leukemia factor
IDI1 isopentenyl-diphosphate delta isomerase 1
IFRD2 interferon-related developmental regulator 2
LDLR low density lipoprotein receptor
LIMCH1 LIM and calponin homology domains 1
LPL lipoprotein lipase
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MLF1 myeloid leukemia factor 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PTX3 pentraxin 3, long
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RBP1 retinol binding protein 1, cellular
RPS11 ribosomal protein S11
SARAF store-operated calcium entry-associated regulatory factor
SIK1 salt-inducible kinase 1
ST7 suppression of tumorigenicity 7
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TCTA T-cell leukemia translocation altered
TM4SF1 transmembrane 4 L six family member 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6

decreased expression

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACTN1 actinin, alpha 1
ADM adrenomedullin
ALCAM activated leukocyte cell adhesion molecule
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANXA1 annexin A1
ARHGAP32 Rho GTPase activating protein 32
CA2 carbonic anhydrase II
CD200 CD200 molecule
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
EFR3A EFR3 homolog A (S. cerevisiae)
ELANE elastase, neutrophil expressed
FAM69A family with sequence similarity 69, member A
FGFR2 fibroblast growth factor receptor 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
HOXB2 homeobox B2
HOXB6 homeobox B6
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ISOC1 isochorismatase domain containing 1
JCHAIN joining chain of multimeric IgA and IgM
MAN2A1 mannosidase, alpha, class 2A, member 1
MYOF myoferlin
OVGP1 oviductal glycoprotein 1, 120kDa
PRRC2C proline-rich coiled-coil 2C
RTN1 reticulon 1
RUFY3 RUN and FYVE domain containing 3
S100A8 S100 calcium binding protein A8
SCGB1D2 secretoglobin, family 1D, member 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SULF1 sulfatase 1
TRIM2 tripartite motif containing 2
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta