BRD-K24686773_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K24686773_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP4 bone morphogenetic protein 4
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CD52 CD52 molecule
CD9 CD9 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CLC Charcot-Leyden crystal galectin
CSTA cystatin A (stefin A)
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GREM1 gremlin 1, DAN family BMP antagonist
KIAA1598
LGALS2 lectin, galactoside-binding, soluble, 2
MOSPD1 motile sperm domain containing 1
MXRA5 matrix-remodelling associated 5
MYRF myelin regulatory factor
NR4A3 nuclear receptor subfamily 4, group A, member 3
OLFM4 olfactomedin 4
PKP2 plakophilin 2
POSTN periostin, osteoblast specific factor
RCAN2 regulator of calcineurin 2
S100A8 S100 calcium binding protein A8
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SNX13 sorting nexin 13
STS steroid sulfatase (microsomal), isozyme S
SULF1 sulfatase 1
XIST X inactive specific transcript (non-protein coding)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
CD59 CD59 molecule, complement regulatory protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EBP emopamil binding protein (sterol isomerase)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GAS1 growth arrest-specific 1
HN1 hematological and neurological expressed 1
HOXC6 homeobox C6
IGFBP4 insulin-like growth factor binding protein 4
KRT10 keratin 10, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LPL lipoprotein lipase
MIA melanoma inhibitory activity
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
PDHX pyruvate dehydrogenase complex, component X
STOM stomatin
SYNM synemin, intermediate filament protein
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TMEM2 transmembrane protein 2
TMEM47 transmembrane protein 47
TNC tenascin C
TSPAN3 tetraspanin 3