BRD-K24564544_AT-CSC-07 BRD-K33720404_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-K24564544_AT-CSC-07 BRD-K33720404_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASS1 argininosuccinate synthase 1
CADM1 cell adhesion molecule 1
CCL4 chemokine (C-C motif) ligand 4
CD9 CD9 molecule
CDK14 cyclin-dependent kinase 14
CEMIP cell migration inducing protein, hyaluronan binding
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
EPAS1 endothelial PAS domain protein 1
FBN2 fibrillin 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FST follistatin
GADD45A growth arrest and DNA-damage-inducible, alpha
GFPT1 glutamine--fructose-6-phosphate transaminase 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
IFI27 interferon, alpha-inducible protein 27
IGFBP3 insulin-like growth factor binding protein 3
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
JAG1 jagged 1
LAMB3 laminin, beta 3
LGALS4 lectin, galactoside-binding, soluble, 4
MFAP5 microfibrillar associated protein 5
PDGFA platelet-derived growth factor alpha polypeptide
PHGDH phosphoglycerate dehydrogenase
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PTN pleiotrophin
PTPN12 protein tyrosine phosphatase, non-receptor type 12
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SQSTM1 sequestosome 1
TRIB3 tribbles pseudokinase 3
UPP1 uridine phosphorylase 1
VGLL4 vestigial-like family member 4

decreased expression

Symbol Name
AK4 adenylate kinase 4
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ATAD2 ATPase family, AAA domain containing 2
CCNA2 cyclin A2
CCNF cyclin F
CDC25A cell division cycle 25A
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPYD dihydropyrimidine dehydrogenase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
HOXC6 homeobox C6
KIF20A kinesin family member 20A
LMNB1 lamin B1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PLBD1 phospholipase B domain containing 1
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRDX2 peroxiredoxin 2
RFC5 replication factor C (activator 1) 5, 36.5kDa
RHOBTB3 Rho-related BTB domain containing 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
TGFB1 transforming growth factor, beta 1
TMEM97 transmembrane protein 97
TRIB2 tribbles pseudokinase 2
TSPAN13 tetraspanin 13