BRD-K24496482_SB590885_SKBR3_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K24496482_SB590885_SKBR3_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ATF3 activating transcription factor 3
BST2 bone marrow stromal cell antigen 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EGR1 early growth response 1
F3 coagulation factor III (thromboplastin, tissue factor)
FHL2 four and a half LIM domains 2
GDF15 growth differentiation factor 15
GSN gelsolin
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
L1CAM L1 cell adhesion molecule
LGALS4 lectin, galactoside-binding, soluble, 4
NRIP1 nuclear receptor interacting protein 1
PLAU plasminogen activator, urokinase
PLK2 polo-like kinase 2
PNKP polynucleotide kinase 3'-phosphatase
PPAP2B phosphatidic acid phosphatase type 2B
RHOBTB3 Rho-related BTB domain containing 3
RND3 Rho family GTPase 3
RPS4Y1 ribosomal protein S4, Y-linked 1
RYR1 ryanodine receptor 1 (skeletal)
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SST somatostatin
STMN2 stathmin 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
AKR1C1 aldo-keto reductase family 1, member C1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASXL2 additional sex combs like transcriptional regulator 2
CADM1 cell adhesion molecule 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL11A1 collagen, type XI, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CSTA cystatin A (stefin A)
CTSC cathepsin C
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FGF13 fibroblast growth factor 13
FOLR1 folate receptor 1 (adult)
GATA2 GATA binding protein 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGHM immunoglobulin heavy constant mu
IGLV3-19 immunoglobulin lambda variable 3-19
IRS2 insulin receptor substrate 2
ITM2A integral membrane protein 2A
MAGEA3 melanoma antigen family A3
MAGED1 melanoma antigen family D1
MNDA myeloid cell nuclear differentiation antigen
POSTN periostin, osteoblast specific factor
SEPHS1 selenophosphate synthetase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPB surfactant protein B
SFTPD surfactant protein D
STK26 serine/threonine protein kinase 26
TARP TCR gamma alternate reading frame protein
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
VCAN versican
VLDLR very low density lipoprotein receptor