BRD-K24496482_SB590885_PC3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K24496482_SB590885_PC3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CD48 CD48 molecule
COL4A1 collagen, type IV, alpha 1
CXORF57 chromosome X open reading frame 57
DUSP10 dual specificity phosphatase 10
FZD6 frizzled class receptor 6
HMBOX1 homeobox containing 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP4 insulin-like growth factor binding protein 4
N4BP2L2 NEDD4 binding protein 2-like 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOTCH2NL notch 2 N-terminal like
NPIPB3 nuclear pore complex interacting protein family, member B3
PRL prolactin
PTGDS prostaglandin D2 synthase 21kDa (brain)
RPS11 ribosomal protein S11
SFRP1 secreted frizzled-related protein 1
STK10 serine/threonine kinase 10
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TUSC3 tumor suppressor candidate 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ALDOB aldolase B, fructose-bisphosphate
BIK BCL2-interacting killer (apoptosis-inducing)
BSG basigin (Ok blood group)
CD24 CD24 molecule
CD9 CD9 molecule
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLK1 delta-like 1 homolog (Drosophila)
E2F2 E2F transcription factor 2
IL7R interleukin 7 receptor
JADE2 jade family PHD finger 2
KIAA1033 KIAA1033
KLF10 Kruppel-like factor 10
KRT20 keratin 20, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTBP1 latent transforming growth factor beta binding protein 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
NRCAM neuronal cell adhesion molecule
PDE4B phosphodiesterase 4B, cAMP-specific
PER2 period circadian clock 2
PI3 peptidase inhibitor 3, skin-derived
POSTN periostin, osteoblast specific factor
POU2AF1 POU class 2 associating factor 1
SEPP1 selenoprotein P, plasma, 1
SLC38A1 solute carrier family 38, member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPP1 secreted phosphoprotein 1
TACSTD2 tumor-associated calcium signal transducer 2
TCF3 transcription factor 3
THBS4 thrombospondin 4
TLR4 toll-like receptor 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIP6 thyroid hormone receptor interactor 6
TSPAN8 tetraspanin 8