BRD-K24496482_SB590885_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K24496482_SB590885_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
ARID5B AT rich interactive domain 5B (MRF1-like)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
DDIT4 DNA-damage-inducible transcript 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FKBP11 FK506 binding protein 11, 19 kDa
GOLGA8A golgin A8 family, member A
GPNMB glycoprotein (transmembrane) nmb
HLA-B major histocompatibility complex, class I, B
IFI27 interferon, alpha-inducible protein 27
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IGLV3-19 immunoglobulin lambda variable 3-19
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INSIG1 insulin induced gene 1
KDM3A lysine (K)-specific demethylase 3A
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAN1A1 mannosidase, alpha, class 1A, member 1
MGP matrix Gla protein
MT1F metallothionein 1F
MT1M metallothionein 1M
MT1X metallothionein 1X
NEFL neurofilament, light polypeptide
QPRT quinolinate phosphoribosyltransferase
REEP1 receptor accessory protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
AREG amphiregulin
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASCL1 achaete-scute family bHLH transcription factor 1
BPI bactericidal/permeability-increasing protein
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EHF ets homologous factor
ELOVL5 ELOVL fatty acid elongase 5
EMP1 epithelial membrane protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
ETV1 ets variant 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCAR Fc fragment of IgA receptor
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GDF15 growth differentiation factor 15
HBEGF heparin-binding EGF-like growth factor
IER3 immediate early response 3
IGFBP7 insulin-like growth factor binding protein 7
JUN jun proto-oncogene
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MNDA myeloid cell nuclear differentiation antigen
MYC v-myc avian myelocytomatosis viral oncogene homolog
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAC8 placenta-specific 8
RGCC regulator of cell cycle
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELL selectin L
SORBS2 sorbin and SH3 domain containing 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TLR4 toll-like receptor 4
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1