BRD-K24496482_SB590885_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

227 genes differentially expressed following the BRD-K24496482_SB590885_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
AKR1C3 aldo-keto reductase family 1, member C3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDOC aldolase C, fructose-bisphosphate
AMACR alpha-methylacyl-CoA racemase
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG1 B-cell translocation gene 1, anti-proliferative
C6ORF48 chromosome 6 open reading frame 48
CALML4 calmodulin-like 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CASP6 caspase 6, apoptosis-related cysteine peptidase
CAT catalase
CD99 CD99 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CFB complement factor B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHMP2A charged multivesicular body protein 2A
CLIC5 chloride intracellular channel 5
COL11A1 collagen, type XI, alpha 1
CRIP1 cysteine-rich protein 1 (intestinal)
CTSB cathepsin B
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEFB1 defensin, beta 1
DENND2D DENN/MADD domain containing 2D
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA1 ephrin-A1
ERBB3 erb-b2 receptor tyrosine kinase 3
F13A1 coagulation factor XIII, A1 polypeptide
FABP1 fatty acid binding protein 1, liver
FOLR1 folate receptor 1 (adult)
FOXO4 forkhead box O4
FUCA1 fucosidase, alpha-L- 1, tissue
GPR137B G protein-coupled receptor 137B
GPX3 glutathione peroxidase 3
HBB hemoglobin, beta
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST3H2A histone cluster 3, H2a
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
IFI27 interferon, alpha-inducible protein 27
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ISG15 ISG15 ubiquitin-like modifier
ITM2C integral membrane protein 2C
KRT20 keratin 20, type I
MAPT microtubule-associated protein tau
MATN2 matrilin 2
MSLN mesothelin
MTMR11 myotubularin related protein 11
MVP major vault protein
MX1 MX dynamin-like GTPase 1
MXI1 MAX interactor 1, dimerization protein
N4BP2L2 NEDD4 binding protein 2-like 2
NEBL nebulette
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NMRK1 nicotinamide riboside kinase 1
NOV nephroblastoma overexpressed
NPC2 Niemann-Pick disease, type C2
NRCAM neuronal cell adhesion molecule
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ORAI3 ORAI calcium release-activated calcium modulator 3
PBLD phenazine biosynthesis-like protein domain containing
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCCA propionyl CoA carboxylase, alpha polypeptide
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEG10 paternally expressed 10
PHYH phytanoyl-CoA 2-hydroxylase
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLCB4 phospholipase C, beta 4
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PROS1 protein S (alpha)
PRUNE2 prune homolog 2 (Drosophila)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPRK protein tyrosine phosphatase, receptor type, K
QPCT glutaminyl-peptide cyclotransferase
RAB17 RAB17, member RAS oncogene family
RBKS ribokinase
REG1A regenerating islet-derived 1 alpha
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE6 ribonuclease, RNase A family, k6
RPS4Y1 ribosomal protein S4, Y-linked 1
RSRP1 arginine/serine-rich protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELENBP1 selenium binding protein 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEPP1 selenoprotein P, plasma, 1
SERF2 small EDRK-rich factor 2
SESN1 sestrin 1
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A18 solute carrier family 22, member 18
SLC35E2B solute carrier family 35, member E2B
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOX4 SRY (sex determining region Y)-box 4
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
SRRM2 serine/arginine repetitive matrix 2
STXBP1 syntaxin binding protein 1
TMPRSS3 transmembrane protease, serine 3
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)
TOX thymocyte selection-associated high mobility group box
TSC22D3 TSC22 domain family, member 3
TSPAN31 tetraspanin 31
TUBA1A tubulin, alpha 1a
TXNIP thioredoxin interacting protein
UGDH UDP-glucose 6-dehydrogenase
WIPI1 WD repeat domain, phosphoinositide interacting 1
YPEL5 yippee-like 5 (Drosophila)

decreased expression

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
BOP1 block of proliferation 1
BTG3 BTG family, member 3
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BYSL bystin-like
CCDC86 coiled-coil domain containing 86
CCNA2 cyclin A2
CCP110 centriolar coiled coil protein 110kDa
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CEP55 centrosomal protein 55kDa
CHEK2 checkpoint kinase 2
CKS1B CDC28 protein kinase regulatory subunit 1B
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
COTL1 coactosin-like F-actin binding protein 1
CPB1 carboxypeptidase B1 (tissue)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DBF4 DBF4 zinc finger
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP6 dual specificity phosphatase 6
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
ENG endoglin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM129A family with sequence similarity 129, member A
FAM216A family with sequence similarity 216, member A
FBL fibrillarin
FOSL1 FOS-like antigen 1
FOXM1 forkhead box M1
FST follistatin
GAL galanin/GMAP prepropeptide
GINS2 GINS complex subunit 2 (Psf2 homolog)
H2AFX H2A histone family, member X
HK2 hexokinase 2
HMGB2 high mobility group box 2
HPRT1 hypoxanthine phosphoribosyltransferase 1
IER3 immediate early response 3
IFRD2 interferon-related developmental regulator 2
ITGA6 integrin, alpha 6
ITGB1BP1 integrin beta 1 binding protein 1
KIF18B kinesin family member 18B
KIF20A kinesin family member 20A
KLHL7 kelch-like family member 7
KRT15 keratin 15, type I
LBR lamin B receptor
LMNB2 lamin B2
LTF lactotransferrin
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MCM10 minichromosome maintenance complex component 10
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MELK maternal embryonic leucine zipper kinase
MMP7 matrix metallopeptidase 7
MRPS2 mitochondrial ribosomal protein S2
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NEK2 NIMA-related kinase 2
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOP16 NOP16 nucleolar protein
NPM3 nucleophosmin/nucleoplasmin 3
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ODC1 ornithine decarboxylase 1
PLK1 polo-like kinase 1
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPIF peptidylprolyl isomerase F
PRC1 protein regulator of cytokinesis 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RANBP1 RAN binding protein 1
RFC3 replication factor C (activator 1) 3, 38kDa
RRM2 ribonucleotide reductase M2
SFRP1 secreted frizzled-related protein 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMC2 structural maintenance of chromosomes 2
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SNX10 sorting nexin 10
SPATS2L spermatogenesis associated, serine-rich 2-like
SRM spermidine synthase
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMPO thymopoietin
TRBC1 T cell receptor beta constant 1
TSPAN4 tetraspanin 4
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
VRK1 vaccinia related kinase 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)