BRD-K24496482_SB590885_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

113 genes differentially expressed following the BRD-K24496482_SB590885_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ACO2 aconitase 2, mitochondrial
ADD3 adducin 3 (gamma)
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AMACR alpha-methylacyl-CoA racemase
ATP10B ATPase, class V, type 10B
ATP9A ATPase, class II, type 9A
ATRX alpha thalassemia/mental retardation syndrome X-linked
BEX4 brain expressed, X-linked 4
C3ORF14 chromosome 3 open reading frame 14
CD24 CD24 molecule
CDH17 cadherin 17, LI cadherin (liver-intestine)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
COMT catechol-O-methyltransferase
CST1 cystatin SN
CXADR coxsackie virus and adenovirus receptor
DEFB1 defensin, beta 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EFNB2 ephrin-B2
FOXO4 forkhead box O4
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GALC galactosylceramidase
GAS6 growth arrest-specific 6
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GJA1 gap junction protein, alpha 1, 43kDa
GPX3 glutathione peroxidase 3
GSN gelsolin
GSTA4 glutathione S-transferase alpha 4
GYG2 glycogenin 2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BD histone cluster 1, H2bd
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HP haptoglobin
IFI6 interferon, alpha-inducible protein 6
KLK11 kallikrein-related peptidase 11
MAGED1 melanoma antigen family D1
MAGED2 melanoma antigen family D2
MATN2 matrilin 2
MVP major vault protein
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX2 neuronal pentraxin II
NUPR1 nuclear protein, transcriptional regulator, 1
PLCB4 phospholipase C, beta 4
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PROM1 prominin 1
PSCA prostate stem cell antigen
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPRK protein tyrosine phosphatase, receptor type, K
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RND3 Rho family GTPase 3
RPL39L ribosomal protein L39-like
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELENBP1 selenium binding protein 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SPINK1 serine peptidase inhibitor, Kazal type 1
SRSF5 serine/arginine-rich splicing factor 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TCTA T-cell leukemia translocation altered
TMEM230 transmembrane protein 230
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPP1 tripeptidyl peptidase I
TSPAN31 tetraspanin 31
TST thiosulfate sulfurtransferase (rhodanese)
YPEL5 yippee-like 5 (Drosophila)
ZBTB10 zinc finger and BTB domain containing 10

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
CGA glycoprotein hormones, alpha polypeptide
CXCR4 chemokine (C-X-C motif) receptor 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP2 dual specificity phosphatase 2
EAPP E2F-associated phosphoprotein
EPCAM epithelial cell adhesion molecule
FAM216A family with sequence similarity 216, member A
FAM46A family with sequence similarity 46, member A
FBL fibrillarin
FOSL1 FOS-like antigen 1
FST follistatin
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IL13RA2 interleukin 13 receptor, alpha 2
IL1RN interleukin 1 receptor antagonist
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LYZ lysozyme
MT2A metallothionein 2A
NID1 nidogen 1
NOP16 NOP16 nucleolar protein
NPM3 nucleophosmin/nucleoplasmin 3
ODC1 ornithine decarboxylase 1
PEG10 paternally expressed 10
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PLP2 proteolipid protein 2 (colonic epithelium-enriched)
PPAT phosphoribosyl pyrophosphate amidotransferase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGS2 regulator of G-protein signaling 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RRP1B ribosomal RNA processing 1B
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SRM spermidine synthase
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
WARS tryptophanyl-tRNA synthetase
YBX3 Y box binding protein 3