BRD-K24496482_SB590885_HS578T_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K24496482_SB590885_HS578T_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
CCND1 cyclin D1
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP6 dual specificity phosphatase 6
E2F2 E2F transcription factor 2
EMP1 epithelial membrane protein 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETV1 ets variant 1
FGF13 fibroblast growth factor 13
FOSL1 FOS-like antigen 1
HMGA2 high mobility group AT-hook 2
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
NRP1 neuropilin 1
NT5E 5'-nucleotidase, ecto (CD73)
NTS neurotensin
PCSK1 proprotein convertase subtilisin/kexin type 1
PEG3 paternally expressed 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PNP purine nucleoside phosphorylase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTX3 pentraxin 3, long
RPS11 ribosomal protein S11
SCG5 secretogranin V
SCML1 sex comb on midleg-like 1 (Drosophila)
SFRP1 secreted frizzled-related protein 1
SPRY4 sprouty homolog 4 (Drosophila)
STC1 stanniocalcin 1
STX1A syntaxin 1A (brain)
TRIB2 tribbles pseudokinase 2
TSPAN5 tetraspanin 5
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADRB2 adrenoceptor beta 2, surface
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CCDC85B coiled-coil domain containing 85B
CD58 CD58 molecule
COL5A1 collagen, type V, alpha 1
CSRP1 cysteine and glycine-rich protein 1
CSRP2 cysteine and glycine-rich protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DDIT4 DNA-damage-inducible transcript 4
DRAM1 DNA-damage regulated autophagy modulator 1
FHL1 four and a half LIM domains 1
GSTT1 glutathione S-transferase theta 1
HACD1 3-hydroxyacyl-CoA dehydratase 1
IFI27 interferon, alpha-inducible protein 27
KRT14 keratin 14, type I
KRT7 keratin 7, type II
LMOD1 leiomodin 1 (smooth muscle)
LUM lumican
MEIS1 Meis homeobox 1
MN1 meningioma (disrupted in balanced translocation) 1
MSMB microseminoprotein, beta-
NEBL nebulette
NQO1 NAD(P)H dehydrogenase, quinone 1
NXN nucleoredoxin
PALLD palladin, cytoskeletal associated protein
POU2AF1 POU class 2 associating factor 1
RHOQ ras homolog family member Q
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
TNS1 tensin 1
TP53I3 tumor protein p53 inducible protein 3
TPD52L1 tumor protein D52-like 1
VAV3 vav 3 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZBED2 zinc finger, BED-type containing 2