BRD-K24496482_SB590885_HEPG2_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K24496482_SB590885_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ANXA1 annexin A1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CAST calpastatin
F2RL1 coagulation factor II (thrombin) receptor-like 1
G0S2 G0/G1 switch 2
GPR137B G protein-coupled receptor 137B
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOMER1 homer scaffolding protein 1
HOXC6 homeobox C6
JADE2 jade family PHD finger 2
LEF1 lymphoid enhancer-binding factor 1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MGLL monoglyceride lipase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
NAV3 neuron navigator 3
NEFL neurofilament, light polypeptide
NRN1 neuritin 1
NRP1 neuropilin 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRKCA protein kinase C, alpha
RAB31 RAB31, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RGS4 regulator of G-protein signaling 4
RHOBTB3 Rho-related BTB domain containing 3
S100A11 S100 calcium binding protein A11
SGK1 serum/glucocorticoid regulated kinase 1
SIRPG signal-regulatory protein gamma
SPINK1 serine peptidase inhibitor, Kazal type 1
SRGN serglycin
STC1 stanniocalcin 1
TBX2 T-box 2
TGM2 transglutaminase 2
TMEM255A transmembrane protein 255A
WSB2 WD repeat and SOCS box containing 2

decreased expression

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK2 adenylate kinase 2
ASRGL1 asparaginase like 1
CCNB2 cyclin B2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFB complement factor B
CGA glycoprotein hormones, alpha polypeptide
CHMP4A charged multivesicular body protein 4A
COL3A1 collagen, type III, alpha 1
CP ceruloplasmin (ferroxidase)
CRIP1 cysteine-rich protein 1 (intestinal)
DHCR24 24-dehydrocholesterol reductase
EYA2 EYA transcriptional coactivator and phosphatase 2
FADS2 fatty acid desaturase 2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FGFR2 fibroblast growth factor receptor 2
GJA1 gap junction protein, alpha 1, 43kDa
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IL17RB interleukin 17 receptor B
KAZN kazrin, periplakin interacting protein
KRT7 keratin 7, type II
NUPR1 nuclear protein, transcriptional regulator, 1
PLAGL1 pleiomorphic adenoma gene-like 1
RGCC regulator of cell cycle
S100A14 S100 calcium binding protein A14
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SOX9 SRY (sex determining region Y)-box 9