BRD-K24496482_SB590885_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K24496482_SB590885_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARL4C ADP-ribosylation factor-like 4C
CD36 CD36 molecule (thrombospondin receptor)
CDC20 cell division cycle 20
CDKN2A cyclin-dependent kinase inhibitor 2A
CPVL carboxypeptidase, vitellogenic-like
CRISP3 cysteine-rich secretory protein 3
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
ETV1 ets variant 1
F5 coagulation factor V (proaccelerin, labile factor)
FAIM Fas apoptotic inhibitory molecule
GLRX glutaredoxin (thioltransferase)
LAPTM4B lysosomal protein transmembrane 4 beta
LPIN1 lipin 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
NELL2 NEL-like 2 (chicken)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PNMA2 paraneoplastic Ma antigen 2
PRKCA protein kinase C, alpha
PRSS2 protease, serine, 2 (trypsin 2)
REG1A regenerating islet-derived 1 alpha
RTN1 reticulon 1
SEPP1 selenoprotein P, plasma, 1
STEAP3 STEAP family member 3, metalloreductase
STX1A syntaxin 1A (brain)
TIAM1 T-cell lymphoma invasion and metastasis 1
TM4SF1 transmembrane 4 L six family member 1

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRG1 adhesion G protein-coupled receptor G1
AKAP12 A kinase (PRKA) anchor protein 12
APOD apolipoprotein D
ATF3 activating transcription factor 3
C8ORF4 chromosome 8 open reading frame 4
CCL2 chemokine (C-C motif) ligand 2
CHRDL1 chordin-like 1
COL14A1 collagen, type XIV, alpha 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
EDN1 endothelin 1
EGF epidermal growth factor
EGR1 early growth response 1
EGR3 early growth response 3
ESR1 estrogen receptor 1
FGFR2 fibroblast growth factor receptor 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GDF15 growth differentiation factor 15
GNLY granulysin
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IL32 interleukin 32
JCHAIN joining chain of multimeric IgA and IgM
JUNB jun B proto-oncogene
KRT17 keratin 17, type I
MATN2 matrilin 2
MCAM melanoma cell adhesion molecule
MT1M metallothionein 1M
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPR3 natriuretic peptide receptor 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NXN nucleoredoxin
PLCB4 phospholipase C, beta 4
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SCGB1D2 secretoglobin, family 1D, member 2
SOD2 superoxide dismutase 2, mitochondrial
THBS1 thrombospondin 1
TMSB15A thymosin beta 15a
TNC tenascin C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10