BRD-K24426149_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-K24426149_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADIRF adipogenesis regulatory factor
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
C1S complement component 1, s subcomponent
C3 complement component 3
C6ORF62 chromosome 6 open reading frame 62
CBR3 carbonyl reductase 3
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DUSP1 dual specificity phosphatase 1
ELANE elastase, neutrophil expressed
FOSL1 FOS-like antigen 1
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGFBP7 insulin-like growth factor binding protein 7
IGKV4-1 immunoglobulin kappa variable 4-1
ISLR immunoglobulin superfamily containing leucine-rich repeat
KLF5 Kruppel-like factor 5 (intestinal)
LCN2 lipocalin 2
LPAR1 lysophosphatidic acid receptor 1
MPO myeloperoxidase
MSLN mesothelin
MT1M metallothionein 1M
ODC1 ornithine decarboxylase 1
OLFM4 olfactomedin 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PRDX2 peroxiredoxin 2
PTX3 pentraxin 3, long
S100P S100 calcium binding protein P
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
WBP5 WW domain binding protein 5

decreased expression

Symbol Name
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
C7 complement component 7
DMXL2 Dmx-like 2
FBP1 fructose-1,6-bisphosphatase 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXB6 homeobox B6
HOXB7 homeobox B7
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LMO3 LIM domain only 3 (rhombotin-like 2)
MAGEA3 melanoma antigen family A3
MARCKS myristoylated alanine-rich protein kinase C substrate
MTA1 metastasis associated 1
PRAME preferentially expressed antigen in melanoma
RGS10 regulator of G-protein signaling 10
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10