BRD-K24132293_PIPLARTINE_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

185 genes differentially expressed following the BRD-K24132293_PIPLARTINE_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AQP9 aquaporin 9
ASPN asporin
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BCHE butyrylcholinesterase
C1QA complement component 1, q subcomponent, A chain
C3AR1 complement component 3a receptor 1
C5AR1 complement component 5a receptor 1
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCL4 chemokine (C-C motif) ligand 4
CD14 CD14 molecule
CD163 CD163 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL6A2 collagen, type VI, alpha 2
CPE carboxypeptidase E
CRP C-reactive protein, pentraxin-related
CYBB cytochrome b-245, beta polypeptide
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
F13A1 coagulation factor XIII, A1 polypeptide
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FOS FBJ murine osteosarcoma viral oncogene homolog
FPR1 formyl peptide receptor 1
FTH1 ferritin, heavy polypeptide 1
G0S2 G0/G1 switch 2
GADD45B growth arrest and DNA-damage-inducible, beta
HBB hemoglobin, beta
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
HMGA1 high mobility group AT-hook 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
ITM2A integral membrane protein 2A
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KRT19 keratin 19, type I
MAN1C1 mannosidase, alpha, class 1C, member 1
MSX1 msh homeobox 1
NELL2 NEL-like 2 (chicken)
PIP prolactin-induced protein
PTPRC protein tyrosine phosphatase, receptor type, C
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
S100A9 S100 calcium binding protein A9
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SNX10 sorting nexin 10
STC1 stanniocalcin 1
TGFB1 transforming growth factor, beta 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM30B transmembrane protein 30B
TYMP thymidine phosphorylase
TYROBP TYRO protein tyrosine kinase binding protein
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMD1 adenosylmethionine decarboxylase 1
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BAG5 BCL2-associated athanogene 5
BHLHE40 basic helix-loop-helix family, member e40
CA12 carbonic anhydrase XII
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CD58 CD58 molecule
CD59 CD59 molecule, complement regulatory protein
CDK19 cyclin-dependent kinase 19
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHSY1 chondroitin sulfate synthase 1
CYB5A cytochrome b5 type A (microsomal)
CYTH1 cytohesin 1
DCK deoxycytidine kinase
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EAPP E2F-associated phosphoprotein
EGR2 early growth response 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP7 fatty acid binding protein 7, brain
FASTKD5 FAST kinase domains 5
FKBP14 FK506 binding protein 14, 22 kDa
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXJ3 forkhead box J3
FZD7 frizzled class receptor 7
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1
GLIPR1 GLI pathogenesis-related 1
GSPT2 G1 to S phase transition 2
GSTP1 glutathione S-transferase pi 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HOXA10 homeobox A10
HOXA5 homeobox A5
HOXC6 homeobox C6
HSPA13 heat shock protein 70kDa family, member 13
ICAM1 intercellular adhesion molecule 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IFI27 interferon, alpha-inducible protein 27
IGF1R insulin-like growth factor 1 receptor
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
JAG1 jagged 1
KAT6A K(lysine) acetyltransferase 6A
KIAA0907 KIAA0907
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
LBR lamin B receptor
LDLR low density lipoprotein receptor
LOX lysyl oxidase
MACF1 microtubule-actin crosslinking factor 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MIS12 MIS12 kinetochore complex component
MME membrane metallo-endopeptidase
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIB nuclear factor I/B
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NNMT nicotinamide N-methyltransferase
NOTCH2 notch 2
NOTCH2NL notch 2 N-terminal like
NPAT nuclear protein, ataxia-telangiectasia locus
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NREP neuronal regeneration related protein
NRIP1 nuclear receptor interacting protein 1
OPN3 opsin 3
PANK3 pantothenate kinase 3
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLSCR4 phospholipid scramblase 4
PRDM2 PR domain containing 2, with ZNF domain
PTX3 pentraxin 3, long
RBM15 RNA binding motif protein 15
RBM7 RNA binding motif protein 7
RNF139 ring finger protein 139
RPP38 ribonuclease P/MRP 38kDa subunit
SACS sacsin molecular chaperone
SAV1 salvador family WW domain containing protein 1
SCAF8 SR-related CTD-associated factor 8
SELE selectin E
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERTAD2 SERTA domain containing 2
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SKAP2 src kinase associated phosphoprotein 2
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD7 SMAD family member 7
SOX4 SRY (sex determining region Y)-box 4
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TM2D3 TM2 domain containing 3
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNS3 tensin 3
TRIM16 tripartite motif containing 16
UGCG UDP-glucose ceramide glucosyltransferase
VCAM1 vascular cell adhesion molecule 1
WEE1 WEE1 G2 checkpoint kinase
ZBTB1 zinc finger and BTB domain containing 1
ZBTB18 zinc finger and BTB domain containing 18
ZFP36L2 ZFP36 ring finger protein-like 2