BRD-K24102129_-666_PHH_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K24102129_-666_PHH_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AUTS2 autism susceptibility candidate 2
CD36 CD36 molecule (thrombospondin receptor)
CDKN2A cyclin-dependent kinase inhibitor 2A
CNPY3 canopy FGF signaling regulator 3
COLEC12 collectin sub-family member 12
FLOT1 flotillin 1
FRY furry homolog (Drosophila)
GATA6 GATA binding protein 6
GFRA1 GDNF family receptor alpha 1
HBB hemoglobin, beta
HLA-DMA major histocompatibility complex, class II, DM alpha
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IRF9 interferon regulatory factor 9
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMP5 lysosomal-associated membrane protein family, member 5
LIMA1 LIM domain and actin binding 1
MPPED2 metallophosphoesterase domain containing 2
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NID1 nidogen 1
PENK proenkephalin
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RHOBTB3 Rho-related BTB domain containing 3
SCGB2A2 secretoglobin, family 2A, member 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TLR4 toll-like receptor 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIB2 tribbles pseudokinase 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACACB acetyl-CoA carboxylase beta
ADI1 acireductone dioxygenase 1
ANXA1 annexin A1
BASP1 brain abundant, membrane attached signal protein 1
BIRC3 baculoviral IAP repeat containing 3
CCL20 chemokine (C-C motif) ligand 20
CCNA2 cyclin A2
CCND2 cyclin D2
CD24 CD24 molecule
CHMP4A charged multivesicular body protein 4A
CHPT1 choline phosphotransferase 1
CLU clusterin
COL1A2 collagen, type I, alpha 2
CP ceruloplasmin (ferroxidase)
CSTA cystatin A (stefin A)
CYCS cytochrome c, somatic
DCN decorin
DICER1 dicer 1, ribonuclease type III
DLD dihydrolipoamide dehydrogenase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FADS1 fatty acid desaturase 1
FXYD2 FXYD domain containing ion transport regulator 2
FXYD3 FXYD domain containing ion transport regulator 3
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KYNU kynureninase
LYPLA1 lysophospholipase I
MRPS16 mitochondrial ribosomal protein S16
MSMB microseminoprotein, beta-
MTF2 metal response element binding transcription factor 2
MYCBP MYC binding protein
NEBL nebulette
NFIB nuclear factor I/B
NPY1R neuropeptide Y receptor Y1
NRIP1 nuclear receptor interacting protein 1
PCDH9 protocadherin 9
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
PSENEN presenilin enhancer gamma secretase subunit
REEP5 receptor accessory protein 5
RPS11 ribosomal protein S11
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A13 S100 calcium binding protein A13
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SFN stratifin
SLPI secretory leukocyte peptidase inhibitor
SQRDL sulfide quinone reductase-like (yeast)
TFPI2 tissue factor pathway inhibitor 2
UBE2K ubiquitin-conjugating enzyme E2K
URI1 URI1, prefoldin-like chaperone
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB20 zinc finger and BTB domain containing 20
ZBTB38 zinc finger and BTB domain containing 38