BRD-K23984367_S1040_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K23984367_S1040_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCL20 chemokine (C-C motif) ligand 20
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL2 chemokine (C-X-C motif) ligand 2
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDIT4 DNA-damage-inducible transcript 4
FGFR3 fibroblast growth factor receptor 3
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
LTB lymphotoxin beta (TNF superfamily, member 3)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NRIP1 nuclear receptor interacting protein 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTX3 pentraxin 3, long
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TNIP1 TNFAIP3 interacting protein 1
TRIB3 tribbles pseudokinase 3
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
AOX1 aldehyde oxidase 1
ASS1 argininosuccinate synthase 1
CDCA4 cell division cycle associated 4
DUSP4 dual specificity phosphatase 4
GAS1 growth arrest-specific 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IRAK1 interleukin-1 receptor-associated kinase 1
IRS2 insulin receptor substrate 2
KIF20A kinesin family member 20A
MGP matrix Gla protein
NFIB nuclear factor I/B
SFRP1 secreted frizzled-related protein 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase