BRD-K23657553_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K23657553_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSM3 acyl-CoA synthetase medium-chain family member 3
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
GAL galanin/GMAP prepropeptide
GUSBP11 glucuronidase, beta pseudogene 11
HLA-B major histocompatibility complex, class I, B
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
JCHAIN joining chain of multimeric IgA and IgM
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
TCF4 transcription factor 4
TRIM2 tripartite motif containing 2
VIM vimentin

decreased expression

Symbol Name
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRB14 growth factor receptor-bound protein 14
MDK midkine (neurite growth-promoting factor 2)
MYBPC1 myosin binding protein C, slow type
S100A11 S100 calcium binding protein A11
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)
ZIC1 Zic family member 1