BRD-K23531129_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

83 genes differentially expressed following the BRD-K23531129_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
APOLD1 apolipoprotein L domain containing 1
ATF3 activating transcription factor 3
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CADM1 cell adhesion molecule 1
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CRABP1 cellular retinoic acid binding protein 1
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
EREG epiregulin
F11R F11 receptor
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GEM GTP binding protein overexpressed in skeletal muscle
GPNMB glycoprotein (transmembrane) nmb
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
KLF6 Kruppel-like factor 6
KLK5 kallikrein-related peptidase 5
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MPZL2 myelin protein zero-like 2
MT1M metallothionein 1M
NAMPT nicotinamide phosphoribosyltransferase
NAV2 neuron navigator 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
RBP1 retinol binding protein 1, cellular
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RND3 Rho family GTPase 3
S100A8 S100 calcium binding protein A8
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SPARCL1 SPARC-like 1 (hevin)
STK38L serine/threonine kinase 38 like
TNC tenascin C
UGDH UDP-glucose 6-dehydrogenase
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
BASP1 brain abundant, membrane attached signal protein 1
CCNF cyclin F
CDC25B cell division cycle 25B
CLGN calmegin
COCH cochlin
COL7A1 collagen, type VII, alpha 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRIP1 cysteine-rich protein 1 (intestinal)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
F5 coagulation factor V (proaccelerin, labile factor)
FAM57A family with sequence similarity 57, member A
FOLR1 folate receptor 1 (adult)
IL17RB interleukin 17 receptor B
IRS2 insulin receptor substrate 2
JCHAIN joining chain of multimeric IgA and IgM
KDM5D lysine (K)-specific demethylase 5D
KRT17 keratin 17, type I
MUC5B mucin 5B, oligomeric mucus/gel-forming
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NR2F1 nuclear receptor subfamily 2, group F, member 1
PHF20 PHD finger protein 20
POU2AF1 POU class 2 associating factor 1
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
RPS11 ribosomal protein S11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)