BRD-K23478508_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

95 genes differentially expressed following the BRD-K23478508_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
APOD apolipoprotein D
ARID4B AT rich interactive domain 4B (RBP1-like)
ARID5B AT rich interactive domain 5B (MRF1-like)
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
BMP2 bone morphogenetic protein 2
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
COL11A1 collagen, type XI, alpha 1
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EFNA1 ephrin-A1
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELANE elastase, neutrophil expressed
ESR1 estrogen receptor 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABPB1 GA binding protein transcription factor, beta subunit 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GPM6A glycoprotein M6A
HBEGF heparin-binding EGF-like growth factor
HCAR3 hydroxycarboxylic acid receptor 3
HES1 hes family bHLH transcription factor 1
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KIAA0226L KIAA0226-like
KLF9 Kruppel-like factor 9
LEF1 lymphoid enhancer-binding factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP2K3 mitogen-activated protein kinase kinase 3
MMP8 matrix metallopeptidase 8
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTS neurotensin
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RGS1 regulator of G-protein signaling 1
RHOB ras homolog family member B
RND3 Rho family GTPase 3
SATB1 SATB homeobox 1
SCD5 stearoyl-CoA desaturase 5
SFRP1 secreted frizzled-related protein 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMAD3 SMAD family member 3
TSPAN7 tetraspanin 7
TUFT1 tuftelin 1
TXNIP thioredoxin interacting protein
YBX3 Y box binding protein 3
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
AHNAK2 AHNAK nucleoprotein 2
ANXA6 annexin A6
C6ORF62 chromosome 6 open reading frame 62
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CSRP1 cysteine and glycine-rich protein 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DLK1 delta-like 1 homolog (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYSL2 dihydropyrimidinase-like 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGN3 high mobility group nucleosomal binding domain 3
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
LAPTM4B lysosomal protein transmembrane 4 beta
MAT2A methionine adenosyltransferase II, alpha
MEF2C myocyte enhancer factor 2C
MSMO1 methylsterol monooxygenase 1
OSBPL10 oxysterol binding protein-like 10
PLK1 polo-like kinase 1
PRUNE2 prune homolog 2 (Drosophila)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
TUBB tubulin, beta class I
VCAN versican