BRD-K23149109_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K23149109_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ACKR3 atypical chemokine receptor 3
ALDOC aldolase C, fructose-bisphosphate
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CD9 CD9 molecule
DDIT4 DNA-damage-inducible transcript 4
DUSP6 dual specificity phosphatase 6
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM162A family with sequence similarity 162, member A
FXYD3 FXYD domain containing ion transport regulator 3
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
KDM3A lysine (K)-specific demethylase 3A
MT1E metallothionein 1E
NDRG1 N-myc downstream regulated 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PGK1 phosphoglycerate kinase 1
PGM1 phosphoglucomutase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RGS2 regulator of G-protein signaling 2
RNMT RNA (guanine-7-) methyltransferase
S100P S100 calcium binding protein P
SCGB2A1 secretoglobin, family 2A, member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TMEM47 transmembrane protein 47
TNIP1 TNFAIP3 interacting protein 1
TXNIP thioredoxin interacting protein
UFM1 ubiquitin-fold modifier 1
VEGFA vascular endothelial growth factor A
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
CCNF cyclin F
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
HMGN3 high mobility group nucleosomal binding domain 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KYNU kynureninase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
PCP4 Purkinje cell protein 4
PODXL podocalyxin-like
PSCA prostate stem cell antigen
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TIPARP TCDD-inducible poly(ADP-ribose) polymerase