BRD-K23027438_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

82 genes differentially expressed following the BRD-K23027438_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADIRF adipogenesis regulatory factor
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ANKRD10 ankyrin repeat domain 10
ASNS asparagine synthetase (glutamine-hydrolyzing)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BTG1 B-cell translocation gene 1, anti-proliferative
CCNA1 cyclin A1
CD86 CD86 molecule
CES1 carboxylesterase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CREG1 cellular repressor of E1A-stimulated genes 1
CXCL8 chemokine (C-X-C motif) ligand 8
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EMP1 epithelial membrane protein 1
FMOD fibromodulin
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
IFI30 interferon, gamma-inducible protein 30
IGFBP5 insulin-like growth factor binding protein 5
JAG1 jagged 1
KRT15 keratin 15, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LMO4 LIM domain only 4
LY96 lymphocyte antigen 96
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MXI1 MAX interactor 1, dimerization protein
NAMPT nicotinamide phosphoribosyltransferase
NMRK1 nicotinamide riboside kinase 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ODC1 ornithine decarboxylase 1
PIR pirin (iron-binding nuclear protein)
PTGES prostaglandin E synthase
PTX3 pentraxin 3, long
RBM47 RNA binding motif protein 47
SCGB1D2 secretoglobin, family 1D, member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
SRGN serglycin
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COL9A3 collagen, type IX, alpha 3
CPA3 carboxypeptidase A3 (mast cell)
EPHA3 EPH receptor A3
FABP1 fatty acid binding protein 1, liver
GNAS GNAS complex locus
GRIA2 glutamate receptor, ionotropic, AMPA 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IGFBP7 insulin-like growth factor binding protein 7
MAP7 microtubule-associated protein 7
MCAM melanoma cell adhesion molecule
MGLL monoglyceride lipase
NR2F1 nuclear receptor subfamily 2, group F, member 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PHACTR2 phosphatase and actin regulator 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PXMP2 peroxisomal membrane protein 2, 22kDa
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TF transferrin
WFDC1 WAP four-disulfide core domain 1
ZIC1 Zic family member 1