BRD-K22832646_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K22832646_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C3ORF14 chromosome 3 open reading frame 14
CD52 CD52 molecule
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEMIP cell migration inducing protein, hyaluronan binding
CLC Charcot-Leyden crystal galectin
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CRIP2 cysteine-rich protein 2
CTSK cathepsin K
EMP1 epithelial membrane protein 1
GREM1 gremlin 1, DAN family BMP antagonist
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
LOX lysyl oxidase
MXRA5 matrix-remodelling associated 5
PCDH17 protocadherin 17
PFDN5 prefoldin subunit 5
POSTN periostin, osteoblast specific factor
PTX3 pentraxin 3, long
SULF1 sulfatase 1
THY1 Thy-1 cell surface antigen
TPSB2 tryptase beta 2 (gene/pseudogene)
TRIM2 tripartite motif containing 2
TXNDC9 thioredoxin domain containing 9

decreased expression

Symbol Name
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BASP1 brain abundant, membrane attached signal protein 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
COL4A5 collagen, type IV, alpha 5
COL4A6 collagen, type IV, alpha 6
CST3 cystatin C
CTSC cathepsin C
CTSH cathepsin H
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
HSPA1A heat shock 70kDa protein 1A
PAPOLA poly(A) polymerase alpha
PARP2 poly (ADP-ribose) polymerase 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PWP1 PWP1 homolog (S. cerevisiae)
REEP5 receptor accessory protein 5
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SOAT1 sterol O-acyltransferase 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRPX sushi-repeat containing protein, X-linked
SVIL supervillin
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa