BRD-K22503835_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K22503835_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
BBX bobby sox homolog (Drosophila)
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C1QTNF3 C1q and tumor necrosis factor related protein 3
C9ORF16 chromosome 9 open reading frame 16
CCNE1 cyclin E1
CD47 CD47 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CGRRF1 cell growth regulator with ring finger domain 1
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
FAM117A family with sequence similarity 117, member A
FOXO4 forkhead box O4
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
IFI6 interferon, alpha-inducible protein 6
IFT57 intraflagellar transport 57
IL17RB interleukin 17 receptor B
INSIG1 insulin induced gene 1
LACTB2 lactamase, beta 2
LPIN1 lipin 1
MAGEB2 melanoma antigen family B2
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MLF1 myeloid leukemia factor 1
NEU1 sialidase 1 (lysosomal sialidase)
NOSIP nitric oxide synthase interacting protein
PLA2G15 phospholipase A2, group XV
PNMA2 paraneoplastic Ma antigen 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKCA protein kinase C, alpha
PRSS2 protease, serine, 2 (trypsin 2)
RAD9A RAD9 homolog A (S. pombe)
SRGN serglycin
TBPL1 TBP-like 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBS2 thrombospondin 2
TUBA1A tubulin, alpha 1a
VCAM1 vascular cell adhesion molecule 1
VWA5A von Willebrand factor A domain containing 5A

decreased expression

Symbol Name
ARID1A AT rich interactive domain 1A (SWI-like)
AUTS2 autism susceptibility candidate 2
C6ORF62 chromosome 6 open reading frame 62
CCL19 chemokine (C-C motif) ligand 19
CCND1 cyclin D1
GABPB1 GA binding protein transcription factor, beta subunit 1
IRS1 insulin receptor substrate 1
KRT14 keratin 14, type I
MECOM MDS1 and EVI1 complex locus
MREG melanoregulin
POGK pogo transposable element with KRAB domain
SFRP1 secreted frizzled-related protein 1
TNS3 tensin 3
ZFP36L2 ZFP36 ring finger protein-like 2