BRD-K22385716_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K22385716_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
CA2 carbonic anhydrase II
CADM1 cell adhesion molecule 1
CLIC5 chloride intracellular channel 5
ENO2 enolase 2 (gamma, neuronal)
FN1 fibronectin 1
G0S2 G0/G1 switch 2
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2AE histone cluster 1, H2ae
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HIST1H4H histone cluster 1, H4h
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
MAOA monoamine oxidase A
MCOLN1 mucolipin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PRUNE2 prune homolog 2 (Drosophila)
RGCC regulator of cell cycle
SQRDL sulfide quinone reductase-like (yeast)
SRGN serglycin
TGFBI transforming growth factor, beta-induced, 68kDa
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TPST2 tyrosylprotein sulfotransferase 2
TSPAN7 tetraspanin 7
WT1 Wilms tumor 1
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AUTS2 autism susceptibility candidate 2
CA12 carbonic anhydrase XII
CLU clusterin
CRISP3 cysteine-rich secretory protein 3
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
GOLM1 golgi membrane protein 1
GPM6B glycoprotein M6B
HES1 hes family bHLH transcription factor 1
HSPB8 heat shock 22kDa protein 8
IGFBP6 insulin-like growth factor binding protein 6
LRRC17 leucine rich repeat containing 17
MBP myelin basic protein
MLPH melanophilin
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NKX3-1 NK3 homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PSCA prostate stem cell antigen
RHOBTB3 Rho-related BTB domain containing 3
RPS11 ribosomal protein S11
SATB1 SATB homeobox 1
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SNX7 sorting nexin 7
SPDEF SAM pointed domain containing ETS transcription factor
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFB3 transforming growth factor, beta 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPD52L1 tumor protein D52-like 1
TRIP6 thyroid hormone receptor interactor 6
TSPAN8 tetraspanin 8
TUSC3 tumor suppressor candidate 3
WFDC2 WAP four-disulfide core domain 2