BRD-K22385716_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K22385716_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG2 BTG family, member 2
CHGB chromogranin B
CLIC4 chloride intracellular channel 4
CSRP1 cysteine and glycine-rich protein 1
FILIP1L filamin A interacting protein 1-like
HIST1H2AC histone cluster 1, H2ac
HIST1H2BG histone cluster 1, H2bg
HIST2H2BE histone cluster 2, H2be
KCTD12 potassium channel tetramerization domain containing 12
MAP7 microtubule-associated protein 7
MYH11 myosin, heavy chain 11, smooth muscle
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRCAM neuronal cell adhesion molecule
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBX3 pre-B-cell leukemia homeobox 3
PEG3 paternally expressed 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POU2AF1 POU class 2 associating factor 1
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PYCARD PYD and CARD domain containing
RNF167 ring finger protein 167
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGRL SH3 domain binding glutamate-rich protein like
TFPI2 tissue factor pathway inhibitor 2
TOX3 TOX high mobility group box family member 3

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATHL1 ATH1, acid trehalase-like 1 (yeast)
CCND1 cyclin D1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSRP2 cysteine and glycine-rich protein 2
DEFB1 defensin, beta 1
EGR1 early growth response 1
EMP1 epithelial membrane protein 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
ICAM3 intercellular adhesion molecule 3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KLF6 Kruppel-like factor 6
LMNB1 lamin B1
MUC1 mucin 1, cell surface associated
NNMT nicotinamide N-methyltransferase
PCOLCE procollagen C-endopeptidase enhancer
SPATS2L spermatogenesis associated, serine-rich 2-like
SPDEF SAM pointed domain containing ETS transcription factor
STK26 serine/threonine protein kinase 26
TGFB3 transforming growth factor, beta 3
TIMP3 TIMP metallopeptidase inhibitor 3
UBE2S ubiquitin-conjugating enzyme E2S